Integration of GC–MS and LC–MS for untargeted metabolomics profiling
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …
scientific community as it is applied in several researches relating to diseases diagnosis …
Modern analytical techniques in metabolomics analysis
A Zhang, H Sun, P Wang, Y Han, X Wang - Analyst, 2012 - pubs.rsc.org
Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …
systematically identify and quantify metabolites from a biological sample. Small-molecule …
Current state-of-the-art of nontargeted metabolomics based on liquid chromatography–mass spectrometry with special emphasis in clinical applications
Metabolomics, as a part of systems biology, has been widely applied in different fields of life
science by studying the endogenous metabolites. The development and applications of …
science by studying the endogenous metabolites. The development and applications of …
Untargeted GC-MS Metabolomics
MEP Papadimitropoulos, CG Vasilopoulou… - … profiling: Methods and …, 2018 - Springer
Untargeted metabolomics refers to the high-throughput analysis of the metabolic state of a
biological system (eg, tissue, biological fluid, cell culture) based on the concentration profile …
biological system (eg, tissue, biological fluid, cell culture) based on the concentration profile …
Current state of the art of mass spectrometry-based metabolomics studies–a review focusing on wide coverage, high throughput and easy identification
Metabolomics aims at the comprehensive assessment of a wide range of endogenous
metabolites and attempts to identify and quantify the attractive metabolites in a given …
metabolites and attempts to identify and quantify the attractive metabolites in a given …
Mass spectrometry‐based metabolomics: applications to biomarker and metabolic pathway research
A Zhang, H Sun, G Yan, P Wang… - Biomedical …, 2016 - Wiley Online Library
Mass spectrometry‐based metabolomics has become increasingly popular in molecular
medicine. High‐definition mass spectrometry (MS), coupled with pattern recognition …
medicine. High‐definition mass spectrometry (MS), coupled with pattern recognition …
Review of recent developments in GC–MS approaches to metabolomics-based research
Background Metabolomics aims to identify the changes in endogenous metabolites of
biological systems in response to intrinsic and extrinsic factors. This is accomplished …
biological systems in response to intrinsic and extrinsic factors. This is accomplished …
Data analysis strategies for targeted and untargeted LC-MS metabolomic studies: Overview and workflow
Data analysis is a very challenging task in LC-MS metabolomic studies. The use of powerful
analytical techniques (eg, high-resolution mass spectrometry) provides high-dimensional …
analytical techniques (eg, high-resolution mass spectrometry) provides high-dimensional …
Challenges in mass spectrometry based targeted metabolomics
T Koal, HP Deigner - Current molecular medicine, 2010 - ingentaconnect.com
The gap of the post-genomic era is increasingly being filled by the metabolomics approach,
comprising a technology for analyzing small molecule endogenous metabolites (≤ 1500 …
comprising a technology for analyzing small molecule endogenous metabolites (≤ 1500 …
Mass spectrometry-based metabolomics for clinical study: Recent progresses and applications
In clinical study, metabolomics aims to characterize the metabolic disturbance at the disease
state using large cohorts and further provides diagnostic evidence at the small molecular …
state using large cohorts and further provides diagnostic evidence at the small molecular …