Argatroban therapy in heparin-induced thrombocytopenia

L Rice, MJ Hursting - Expert Review of Clinical Pharmacology, 2008 - Taylor & Francis
Argatroban is a direct thrombin inhibitor approved for anticoagulation in heparin-induced
thrombocytopenia (HIT; in several countries) and in patients with or at risk of HIT undergoing …

Argatroban: a review of its use in the management of heparin-induced thrombocytopenia

S Dhillon - American journal of cardiovascular drugs, 2009 - Springer
Argatroban, a highly selective direct thrombin inhibitor, is indicated for use as an
anticoagulant for the treatment and prophylaxis of thrombosis in patients with heparin …

Update on argatroban for the prophylaxis and treatment of heparin-induced thrombocytopenia type II

E Grouzi - Journal of Blood Medicine, 2014 - Taylor & Francis
Heparin-induced thrombocytopenia (HIT) is a rare but potentially severe complication of
heparin therapy that is strongly associated with venous and arterial thrombosis (HIT and …

Reducing harm associated with anticoagulation: practical considerations of argatroban therapy in heparin-induced thrombocytopenia

MJ Hursting, J Soffer - Drug safety, 2009 - Springer
Argatroban is a hepatically metabolized, direct thrombin inhibitor used for prophylaxis or
treatment of thrombosis in heparin-induced thrombocytopenia (HIT) and for patients with or …

Argatroban therapy in heparin-induced thrombocytopenia

L Rice, M Beiderlinden, MJ Hursting - Heparin-induced …, 2012 - taylorfrancis.com
When heparin-induced thrombocytopenia (HIT) is reasonably suspected, all heparin
exposures should be eliminated and an alternative nonheparin anticoagulant expeditiously …

Safety and efficacy of argatroban in patients with heparin-induced thrombocytopenia.

WH Matthai Jr - Current Hematology Reports, 2006 - europepmc.org
Argatroban is a synthetic direct thrombin inhibitor. It is indicated for use in patients with
heparin-induced thrombocytopenia (HIT). The greatest experience is in prevention and …

Argatroban in the management of heparin-induced thrombocytopenia

L Babuin, V Pengo - Vascular health and risk management, 2010 - Taylor & Francis
Heparin-induced thrombocytopenia (HIT) is an immunoglobulin-mediated serious
complication of heparin therapy characterized by thrombocytopenia and high risk for venous …

Argatroban therapy in heparin-induced thrombocytopenia

BE Lewis, MJ Hursting - Heparin-induced thrombocytopenia, 2007 - taylorfrancis.com
The elimination of all heparin sources and the initiation of alternative anticoagulation are
recommended for treating patients with heparin-induced thrombocytopenia (HIT), whether or …

Argatroban use in heparin-induced thrombocytopenia

LN Boggio, VM Oza - Expert Opinion on Pharmacotherapy, 2008 - Taylor & Francis
Background: Heparin-induced thrombocytopenia (HIT) is a serious, life-threatening
complication which occurs in 1–3% of patients receiving heparin. Patients with untreated HIT …

Argatroban for prevention and treatment of thromboembolism in heparin-induced thrombocytopenia

LM Kondo, AK Wittkowsky… - Annals of …, 2001 - journals.sagepub.com
OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, adverse events, and
cost of argatroban in the prevention and treatment of thromboembolism in patients with …