Novel curcumin-resveratrol solid nanoparticles synergistically inhibit proliferation of melanoma cells

GH Palliyage, N Hussein, M Mimlitz, C Weeder… - Pharmaceutical …, 2021 - Springer
Polyphenols such as curcumin (Cur) and resveratrol (Res) have been recently shown to
have potential to inhibit proliferation of highly aggressive melanoma cells. This study was …

Resveratrol-loaded nanocapsules inhibit murine melanoma tumor growth

B Carletto, J Berton, TN Ferreira, LF Dalmolin… - Colloids and Surfaces B …, 2016 - Elsevier
In this study, resveratrol-loaded nanocapsules were developed and its antitumor activity
tested on a melanoma mice model. These nanocapsules were spherically-shaped and …

Curcumin-loaded solid lipid nanoparticles have prolonged in vitro antitumour activity, cellular uptake and improved in vivo bioavailability

J Sun, C Bi, HM Chan, S Sun, Q Zhang… - Colloids and surfaces b …, 2013 - Elsevier
Purpose The aim of the present study was to blend liquid lipids with solid lipids to
encapsulate curcumin in solid lipid nanoparticles (SLNs), thereby improving the …

Surface modification of solid lipid nanoparticles for oral delivery of curcumin: Improvement of bioavailability through enhanced cellular uptake, and lymphatic uptake

JS Baek, CW Cho - European Journal of Pharmaceutics and …, 2017 - Elsevier
Curcumin has been reported to exhibit potent anticancer effects. However, poor solubility,
bioavailability and stability of curcumin limit its in vivo efficacy for the cancer treatment. Solid …

The evidence for solid lipid nanoparticles mediated cell uptake of resveratrol

K Teskač, J Kristl - International journal of pharmaceutics, 2010 - Elsevier
The potential for colloidal carriers to increase drug bioavailability has spurred a renewed
interest in their uptake mechanisms and movement within cells. Solid lipid nanoparticles …

Formulation of the novel structure curcumin derivative–loaded solid lipid nanoparticles: synthesis, optimization, characterization and anti-tumor activity screening in …

K Li, C Pi, J Wen, Y He, J Yuan, H Shen, W Zhao… - Drug Delivery, 2022 - Taylor & Francis
This study investigated the effect of structural modification of Curcumin (CU) combined with
the solid lipid nanoparticles (SLN) drug delivery system on anti-tumor activity in vitro. A new …

[HTML][HTML] Preparation of curcumin-loaded liposomes and evaluation of their skin permeation and pharmacodynamics

Y Chen, Q Wu, Z Zhang, L Yuan, X Liu, L Zhou - Molecules, 2012 - mdpi.com
This study aimed to investigate the in vitro skin permeation and in vivo antineoplastic effect
of curcumin by using liposomes as the transdermal drug-delivery system. Soybean …

Curcumin-loaded lipid and polymeric nanocapsules stabilized by nonionic surfactants: an in vitro and in vivo antitumor activity on B16-F10 melanoma and …

L Mazzarino, LFC Silva, JC Curta… - Journal of …, 2011 - ingentaconnect.com
Curcumin is a polyphenol obtained from the plant Curcuma longa (called turmeric) that
displays several pharmacological activities, including anti-inflammatory, antioxidant …

Lipid-and polymer-based nanostructures for cutaneous delivery of curcumin

T Caon, L Mazzarino, CMO Simões, EL Senna… - AAPS …, 2017 - Springer
It is well-known that nanoencapsulation may overcome biopharmaceutical limitations of
curcumin (CUR), but studies regarding the contribution of the vesicular nature of CUR …

Synthesis and characterization of curcumin loaded polymer/lipid based nanoparticles and evaluation of their antitumor effects on MCF-7 cells

SSD Kumar, A Mahesh, S Mahadevan… - Biochimica et Biophysica …, 2014 - Elsevier
Background Hybrid materials are synthesized using hydrophilic polymer and lipids which
ensure their long term systemic circulation through intravenous administration and enhance …