Preparation of triamcinolone acetonide-loaded chitosan/fucoidan hydrogel and its potential application as an oral mucosa patch

W Zheng, Y Hao, D Wang, H Huang, F Guo, Z Sun… - Carbohydrate …, 2021 - Elsevier
Oral inflammatory diseases (OIDs) are among the most common lesions in the oral cavity,
affecting the quality of human life and even causing oral cancer. However, most of the …

Enhanced permeation of triamcinolone acetonide through the buccal mucosa

SC Shin, JY Kim - European journal of pharmaceutics and …, 2000 - Elsevier
To develop new formulations that have suitable bioadhesive force and provide sustained
release in buccal area for an extended period of time, bioadhesive gels containing …

Probiotic-loaded calcium alginate/fucoidan hydrogels for promoting oral ulcer healing

X Dou, G Li, S Wang, D Shao, D Wang, X Deng… - International Journal of …, 2023 - Elsevier
Probiotics are beneficial bacteria located in the oral cavity which exhibit antimicrobial
properties and contribute to the regulation of immune function and the modulation of tissue …

Chitosan-based therapeutic systems and their potentials in treatment of oral diseases

H Gao, N Wu, N Wang, J Li, J Sun, Q Peng - International Journal of …, 2022 - Elsevier
The increasing morbidity of oral diseases, such as dental caries, periodontitis and oral
cancer, has greatly compromised the life quality of humans. With the rapid development of …

Enhanced bioavailability by buccal administration of triamcinolone acetonide from the bioadhesive gels in rabbits

SC Shin, JP Bum, JS Choi - International journal of pharmaceutics, 2000 - Elsevier
The pharmacokinetics and bioavailability of triamcinolone acetonide were determined to
investigate buccal absorption from the mucoadhesive gels in rabbits. The enhancing effect …

Characterization of Chitosan‐Gallic Acid Graft Copolymer for Periodontal Dressing Hydrogel Application

M Feng, X Zeng, Q Lin, Y Wang, H Wei… - Advanced …, 2024 - Wiley Online Library
The postoperative periodontal wound is in a complex physiological environment; the
bacteria accumulation, the saliva stimulation, and the food residues retention will aggravate …

Wound healing and antibacterial chitosan-genipin hydrogels with controlled drug delivery for synergistic anti-inflammatory activity

JA Del Olmo, L Pérez-Álvarez, V Sáez-Martínez… - International Journal of …, 2022 - Elsevier
Chitosan (CHI) based hydrogels promote wound healing and relieve inflammations and
chronic infections. However, in hardly healable ulcers with excessively painful …

Janus mucosal dressing with a tough and adhesive hydrogel based on synergistic effects of gelatin, polydopamine, and nano-clay

H An, Z Gu, L Zhou, S Liu, C Li, M Zhang, Y Xu… - Acta Biomaterialia, 2022 - Elsevier
There are many problems and challenges related to the treatment of highly prevalent oral
mucosal diseases and oral drug delivery because of a large amount of saliva present in the …

An injectable multifunctional thermo-sensitive chitosan-based hydrogel for periodontitis therapy

S Ma, X Lu, X Yu, Y Du, S Xu, M Li, C Peng, Z Liu… - Biomaterials …, 2022 - Elsevier
Bacteria are recognized as the driving factors of periodontitis. However, excessive reactive
oxygen species (ROS) can harm periodontal tissue while also causing an uncontrolled …

Injectable adhesive hydrogel through a microcapsule cross-link for periodontitis treatment

Z Dong, Y Sun, Y Chen, Y Liu, C Tang… - ACS Applied Bio …, 2019 - ACS Publications
In this work, chitosan (CS) decorated metronidazole (MTZ) microcapsules (CS@ MTZ) were
synthesized and used as a cross-linker for the preparation of a poly (vinyl alcohol)(PVA) …