The emergence of drug resistance in pathogenic microorganisms provides an excellent
example of microbial evolution that has had profound consequences for human health. The …

The emergence of drug resistance in microbial pathogens provides a poignant example of
an evolutionary process with a profound impact on human health. Fungal drug resistance …

The evolution of drug resistance in fungal pathogens compromises the efficacy of the limited
number of antifungal drugs. Drug combinations have emerged as a powerful strategy to …

Like other microorganisms, fungi exist in populations that are adaptable. Under the selection
imposed by antifungal drugs, drug-sensitive fungal pathogens frequently evolve resistance …

The survival of all organisms depends critically upon interactions with the environment,
mediated largely through the action of small molecules. Small molecules can provide the …

Hsp90 is a molecular chaperone for many signal transducers and may influence evolution
by releasing previously silent genetic variation in response to environmental change. In …

The evolution of drug resistance threatens human health worldwide. An emerging strategy to
mitigate drug resistance is combination therapy. The fate of multidrug-resistant pathogens …

The evolution of drug resistance in microbial pathogens provides a paradigm for
investigating evolutionary dynamics with important consequences for human health …

Highlights•Our limited arsenal of antifungals is threatened by drug-resistant fungal
pathogens.•Inherent resistance is when all strains of a species show antifungal …

Opportunistic fungal pathogens can cause a diverse range of diseases in humans. The
increasing rate of fungal infections caused by strains that are resistant to commonly used …