The hypothalamic-pituitary-adrenocortical (HPA) axis is required to restore homeostasis
during stress, and corticotropin-releasing hormone (CRH) is a key hypothalamic hormone …

We have previously observed significant, albeit decreased, corticosterone responses to
restraint stress in corticotropin releasing hormone (CRH)-deficient (knockout, CRH KO) …

The importance of restraining stress‐induced activation of the hypothalamic‐pituitary‐
adrenocortical (HPA) system within tolerable limits requires efficient mechanisms for …

Corticotropin releasing hormone (CRH) coordinates behavioral, autonomic and hormonal
responses to stress, including activation of the hypothalamic–pituitary–adrenal (HPA) axis …

Glucocorticoid hormones exert a multitude of functions that affect virtually every cell in
thebody. The physiological significance of glucocorticoids is most remarkable at times of …

Corticotropin-releasing hormone (CRH) is a key regulator of the mammalian stress
response, mediating a wide variety of stress-associated behaviors including stress-induced …

Based on pharmacological studies, corticotropin-releasing hormone (CRH) and its receptors
play a leading role in the inhibition of the hypothalamic–pituitary–gonadal (HPG) axis during …

In response to everyday life stress, some individuals readily develop reproductive
dysfunction (ie, they are stress sensitive), whereas others are more stress resilient. When …

Corticotrophin‐releasing hormone (CRH) regulates acute stress‐induced changes in
neuroendocrine function and behaviour. However, little is known about CRH functions in …

During postnatal development, mice undergo a so-called stress hyporesponsive period,
which is characterized by low basal corticosterone levels and the inability of mild stressors to …