Background. A wearable artificial lung could improve lung transplantation outcomes by
easing implementation of physical rehabilitation during long-term pretransplant respiratory …

BACKGROUND: The purpose of this study was to evaluate the long-term in-vivo
hemodynamics, gas transfer, and biocompatibility of an integrated artificial pump-lung (APL) …

Background Conventional extracorporeal membrane oxygenation (ECMO) is cumbersome
and is associated with high morbidity and mortality. We are currently developing the …

Recent studies show improved outcomes in ambulated lung failure patients. Ambulation still
remains a challenge in these patients. This necessitates development of more compact and …

BACKGROUND: Conventional extracorporeal membrane oxygenation is bulky and non-
ambulatory and requires multiple blood transfusions. We hypothesized that a percutaneous …

Respiratory failure is one of the major causes of mortality and morbidity all over the world.
Therapeutic options to treat respiratory failure remain limited. The objective of this study was …

Abstract A new, lightweight (2.3 kg), ambulatory pulmonary assist system (PAS) underwent
preliminary evaluation in ambulatory sheep. The PAS was purposefully designed for long …

BACKGROUND: To provide long-term ambulatory cardiopulmonary and respiratory support
for adult patients, a novel wearable artificial pump-lung device has been developed. The …

BACKGROUND: A thoracic artificial lung, the MC3 Biolung, is being developed as a bridge
to lung transplantation or as a treatment for acute respiratory insufficiency. METHODS: The …

The scarcity of donor organs has led to the development of devices that provide optimal long‐
term respiratory or cardiopulmonary support to bridge recipients as they wait for lung and/or …