A characteristic sign of zinc deficiency is retarded skeletal growth, but the role of zinc in
osteoblasts is not well understood. Two major events for bone formation include osteoblast …

The crucial trace element zinc stimulates osteogenesis in vitro and in vivo. However, the
pathways mediating these effects remain poorly understood. This study aimed to investigate …

The effects of Zinc (Zn)-deficiency on the function and differentiation of osteoblasts and
osteoclasts were investigated in vivo using rats, which were fed a Zn-adequate (control) or …

Zinc is a micronutrient of key importance for human health. An increasing number of studies
indicate that zinc plays a significant role in bone tissue's normal development and …

Zinc is known as an essential nutritional factor in the growth of the human and animals.
Bone growth retardation is a common finding in various conditions associated with dietary …

Disturbed zinc (Zn) homeostasis in mammals is mainly characterized by impaired bone
generation accompanied with growth retardation. However, the underlying mechanisms that …

Zinc (Zn) supplementation stimulates bone growth in Zn-deficient humans and animals. A
biphasic pattern of mineralization has been observed in cultured osteoblasts; an initiation …

Zinc is an essential trace element required for bone formation, however not much has been
clarified yet for its role in osteoblast. We hypothesized that zinc would increase osteogenetic …

Background To this day, empirical data suggests that zinc has important roles in matrix
synthesis, bone turnover, and mineralization and its beneficial effects on bone could be …

The effect of zinc sulfate on the mRNA expressions in Runx2, osteocalcin, α1 (I) collagen,
insulin-like growth factor-I (IGF-I), transforming growth factor-β1 (TGF-β1), osteoprotegerin …