Abstract Oxindole (indoline-2, 3-dione) has been utilized to a great extent in heterocyclic
scaffold syntheses as a futuristic medication and is considered a prominent building block …

Spiroindole and spirooxindole scaffolds are very important spiro-heterocyclic compounds in
drug design processes. Significant attention has been directed at obtaining molecules …

Spirocyclopropyl oxindole represents an emerging framework by unique amalgamation of
versatile 2‐oxindole motif and highly strained cyclopropane unit. This scaffold is remarkable …

A concise and efficient one-pot regio-and stereoselective synthesis of structurally diverse
spirooxindoles was constructed by simply refluxing a mixture of different types of …

Highly divergent complexity molecules, having spirooxindole core structure, possess
excellent bioactivities. The 1, 3‐dipolar cycloaddition reaction is one of the most efficient …

Oxindoles and spirooxindoles are important synthetic targets that are often considered to be
prevalidated with respect to their biological activity and applications for pharmaceutical lead …

A collection of structurally complex and chemically diverse small molecules is a useful tool to
explore cell circuitry. In this article, we have reported the two step synthesis of diverse …

Spiroindolines and spiroindoles are an important class of spirocyclic compounds present in
a wide range of pharmaceuticals and biologically important natural alkaloids. Various …

Spirooxindoles occupy an important place in heterocyclic chemistry. Many natural
spirooxindole-containing compounds have been identified as bio-promising agents …

The role of oxindole derivatives is discussed as starting materials in diverse organic
reactions, including two and more components, between the years 2014 until 2020 …