[HTML][HTML] CAR-NK cells in the treatment of solid tumors

E Wrona, M Borowiec, P Potemski - International journal of molecular …, 2021 - mdpi.com
CAR-T (chimeric antigen receptor T) cells have emerged as a milestone in the treatment of
patients with refractory B-cell neoplasms. However, despite having unprecedented efficacy …

[HTML][HTML] From CAR-T cells to CAR-NK cells: a developing immunotherapy method for hematological malignancies

H Lu, X Zhao, Z Li, Y Hu, H Wang - Frontiers in Oncology, 2021 - frontiersin.org
The approval of CD19 chimeric antigen receptor (CAR)-engineered T (CAR-T) cell products
in B-cell malignancies represents a breakthrough in CAR-T cell immunotherapy. However …

[HTML][HTML] Preclinical and clinical studies of CAR-NK-cell therapies for malignancies

H Li, W Song, Z Li, M Zhang - Frontiers in Immunology, 2022 - frontiersin.org
The development of chimeric antigen receptor T (CAR-T) cell therapy, a specific type of
immunotherapy, in recent decades was a fantastic breakthrough for the treatment of …

Novel insights in CAR-NK cells beyond CAR-T cell technology; promising advantages

H Ebrahimiyan, A Tamimi, B Shokoohian… - International …, 2022 - Elsevier
CAR-T (chimeric antigen receptor T cell) technology, which has recently showed successful
results in the treatment of hematological tumors, has been the focus of attention as one of …

[HTML][HTML] CAR-engineered NK cells; a promising therapeutic option for treatment of hematological malignancies

F Marofi, MM Saleh, HS Rahman, W Suksatan… - Stem cell research & …, 2021 - Springer
Adoptive cell therapy has received a great deal of interest in the treatment of advanced
cancers that are resistant to traditional therapy. The tremendous success of chimeric antigen …

CAR‐NK cell in cancer immunotherapy; A promising frontier

F Marofi, OF Abdul‐Rasheed, HS Rahman… - Cancer …, 2021 - Wiley Online Library
Chimeric antigen receptors (CARs) have a unique facet of synthetic biology and offer a
paradigm shift in personalized medicine as they can use and redirect the patient's immune …

[HTML][HTML] CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances

KM Maalej, M Merhi, VP Inchakalody, S Mestiri… - Molecular Cancer, 2023 - Springer
In the last decade, Chimeric Antigen Receptor (CAR)-T cell therapy has emerged as a
promising immunotherapeutic approach to fight cancers. This approach consists of …

Current progress of chimeric antigen receptor (CAR) T versus CAR NK cell for immunotherapy of solid tumors

A Esmaeilzadeh, K Hadiloo, M Jabbari, R Elahi - Life Sciences, 2023 - Elsevier
Equipping cancer-fighting immune cells with chimeric antigen receptor (CAR) has gained
immense attention for cancer treatment. CAR-engineered T cells (CAR T cells) are the first …

[HTML][HTML] CAR-NK cells: a chimeric hope or a promising therapy?

M Sabbah, L Jondreville, C Lacan, F Norol, V Vieillard… - Cancers, 2022 - mdpi.com
Simple Summary In recent years, innovative immunotherapy-based treatments have paved
the way for a new approach to hematological malignancies. Instead of conventional …

[HTML][HTML] CAR-NK for tumor immunotherapy: Clinical transformation and future prospects

W Wang, J Jiang, C Wu - Cancer letters, 2020 - Elsevier
Recently, the use of chimeric antigen receptor-modified T (CAR-T)-cells in the treatment of
hematological tumors has been successful and has become a clinical hotspot in tumor …