The brain of Drosophila melanogaster is comprised of some 100,000 neurons, 127 and 80
of which are dopaminergic and serotonergic, respectively. Their activity regulates behavioral …

The ability of Drosophila genetics to reveal new insights into human neurodegenerative
disease is highlighted not only by mutants in flies that show neuronal cell loss, but also by …

Neurodegenerative diseases represent a formidable challenge to global health. As
advances in other areas of medicine grant healthy living into later decades of life, aging …

Central nervous system (CNS) drug discovery in the post-genomic era is rapidly evolving.
Older empirical methods are giving way to newer technologies that include bioinformatics …

For decades, Drosophila melanogaster has been used as a model organism to study human
diseases, ranging from heart disease to cancer to neurological disorders [9]. For studying …

Introduction: Drosophila melanogaster offers a powerful expedient and economical system
with facile genetics. Because of the high sequence and functional conservation with human …

The fruit fly Drosophila melanogaster is a powerful genetic model organism, which has been
instrumental in the determination of essential developmental and neurological pathways …

Fruits, vegetables, and spices are natural sources of bioactive phytochemicals, such as
polyphenols, carotenoids, flavonoids, curcuminoids, terpenoids, and capsaicinoids …

Glial cells are key players in the proper formation and maintenance of the nervous system,
thus contributing to neuronal health and disease in humans. However, little is known about …

As populations benefit from increasing lifespans, neurodegenerative diseases have
emerged as a critical health concern. How can the fruit fly, Drosophila melanogaster …