Metals are indispensable for the life of all organisms, and their dysregulation leads to
various disorders due to the disruption of their homeostasis. Nowadays, various transition …

The peculiar chemical properties of metal-based drugs impart innovative pharmacological
profiles to this class of therapeutic and diagnostic agents, most likely in relation to novel …

Metal-based compounds form a promising class of therapeutic agents, whose mechanisms
of action still need to be elucidated, and that are in general prone to undergo extensive …

The behavior of metals and metallodrugs in biological systems affects the setup of
therapeutic strategies with a distinct mode of action and new knowledge of clinically-proven …

The clinical application and development of potent metal-based drugs relies heavily on a full
understanding of their underlying molecular mechanisms. The emerging research field of …

Medicinal inorganic chemistry has been largely stimulated by the clinic success of platinum
anticancer drugs. An array of metal-based drugs (eg platinum, gold, bismuth, and silver) are …

Metals play vital roles in nutrients and medicines and provide chemical functionalities that
are not accessible to purely organic compounds. At least 10 metals are essential for human …

The peculiar chemical properties of metal-based drugs impart innovative pharmacological
profiles to this class of therapeutic and diagnostic agents, most likely in relation to novel …

Known as highly efficient metallodrugs that have been clinically used to treat various types
of cancers, cisplatin and its analogues have attracted and inspired extensive interest in the …

Metal-based drugs and imaging agents are extensively used in the clinic for the treatment
and diagnosis of cancers and a wide range of other diseases. The current clinical arsenal of …