The intersection of capsule gene expression, hypermucoviscosity and hypervirulence in Klebsiella pneumoniae
KA Walker, VL Miller - Current opinion in microbiology, 2020 - Elsevier
For∼ 30 years, two distinct groups of clinical isolates of Klebsiella pneumoniae have been
recognized. Classical strains (cKp) are typically isolated from patients with some degree of …
recognized. Classical strains (cKp) are typically isolated from patients with some degree of …
The contribution of capsule polysaccharide genes to virulence of Klebsiella pneumoniae
KS Ko - Virulence, 2017 - Taylor & Francis
Klebsiella pneumoniae is a Gram-negative, non-motile bacterium that is found in the
environment, including in soil and surface water. K. pneumoniae readily colonizes human …
environment, including in soil and surface water. K. pneumoniae readily colonizes human …
Identification of Two Regulators of Virulence That Are Conserved in Klebsiella pneumoniae Classical and Hypervirulent Strains
M Palacios, TA Miner, DR Frederick, VE Sepulveda… - MBio, 2018 - Am Soc Microbiol
Klebsiella pneumoniae is widely recognized as a pathogen with a propensity for acquiring
antibiotic resistance. It is capable of causing a range of hospital-acquired infections (urinary …
antibiotic resistance. It is capable of causing a range of hospital-acquired infections (urinary …
A Klebsiella pneumoniae regulatory mutant has reduced capsule expression but retains hypermucoviscosity
KA Walker, TA Miner, M Palacios, D Trzilova… - MBio, 2019 - Am Soc Microbiol
The polysaccharide capsule is an essential virulence factor for Klebsiella pneumoniae in
both community-acquired hypervirulent strains as well as health care-associated classical …
both community-acquired hypervirulent strains as well as health care-associated classical …
Assessment of hypermucoviscosity as a virulence factor for experimental Klebsiella pneumoniaeinfections: comparative virulence analysis with hypermucoviscosity …
Background Klebsiella pneumoniae displaying the hypermucoviscosity (HV) phenotype are
considered more virulent than HV-negative strains. Nevertheless, the emergence of tissue …
considered more virulent than HV-negative strains. Nevertheless, the emergence of tissue …
Cell envelope defects of different capsule‐null mutants in K1 hypervirulent Klebsiella pneumoniae can affect bacterial pathogenesis
Hypervirulent Klebsiella pneumoniae (hvKP) causes Klebsiella‐induced liver abscess.
Capsule is important for the pathogenesis of Klebsiella in systemic infection, but its role in …
Capsule is important for the pathogenesis of Klebsiella in systemic infection, but its role in …
Genetic exchange of determinants for capsular polysaccharide biosynthesis between Klebsiella pneumoniae strains expressing serotypes K2 and K21a
I Ofek, K Kabha, A Athamna, G Frankel… - Infection and …, 1993 - Am Soc Microbiol
The production of a capsular polysaccharide (CPS; K antigen) is characteristic of Klebsiella
pneumoniae, but CPS structure varies among strains, and many different serotypes are now …
pneumoniae, but CPS structure varies among strains, and many different serotypes are now …
Capsular Types of Klebsiella pneumoniae Revisited by wzc Sequencing
YJ Pan, TL Lin, YH Chen, CR Hsu, PF Hsieh, MC Wu… - PloS one, 2013 - journals.plos.org
Capsule is an important virulence factor in bacteria. A total of 78 capsular types have been
identified in Klebsiella pneumoniae. However, there are limitations in current typing …
identified in Klebsiella pneumoniae. However, there are limitations in current typing …
Hypervirulent Klebsiella pneumoniae: the Next Superbug?
AS Shon, TA Russo - Future microbiology, 2012 - Taylor & Francis
Future Microbiol.(2012) 7 (6) 670 future science group compromise (eg, neutropenia). Our
laboratory began studying hvKP after a case of CA-PLA with metastatic spread to the spleen …
laboratory began studying hvKP after a case of CA-PLA with metastatic spread to the spleen …
Role of capsule in Klebsiella pneumoniae virulence: lack of correlation between in vitro and in vivo studies
C Struve, KA Krogfelt - FEMS microbiology letters, 2003 - academic.oup.com
In vitro and in vivo models were used to investigate the role of capsule on the virulence of
Klebsiella pneumoniae. We showed that capsule expression reduces dramatically the ability …
Klebsiella pneumoniae. We showed that capsule expression reduces dramatically the ability …
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