Insights into the mechanisms of action of proanthocyanidins and anthocyanins in the treatment of nicotine-induced non-small cell lung cancer

NA Alsharairi - International journal of molecular sciences, 2022 - mdpi.com
In traditional medicine, different parts of plants, including fruits, have been used for their anti-
inflammatory and anti-oxidative properties. Plant-based foods, such as fruits, seeds and …

Quercetin derivatives as potential therapeutic agents: an updated perspective on the treatment of nicotine-induced non-small cell lung cancer

NA Alsharairi - International Journal of Molecular Sciences, 2023 - mdpi.com
Flavonoids are the largest group of polyphenols, represented by many compounds that
exhibit high anticancer properties. Quercetin (Q) and its main derivatives (rutin, quercitrin …

The ameliorating effects of anthocyanins on the cross-linked signaling pathways of cancer dysregulated metabolism

S Fakhri, M Khodamorady, M Naseri, MH Farzaei… - Pharmacological …, 2020 - Elsevier
Cancer cells underlie the dysregulated metabolism of carbohydrate, lipid and protein and
thereby, employ interconnected cross-linked signaling pathways to supply adequate energy …

[HTML][HTML] Procyanidins mediates antineoplastic effects against non-small cell lung cancer via the JAK2/STAT3 pathway

Y Wu, C Liu, Y Niu, J Xia, L Fan, Y Wu… - Translational Cancer …, 2021 - ncbi.nlm.nih.gov
Background Lung cancer is a malignant tumor with one of the highest rates of cancer-related
morbidity and mortality worldwide. Non-small cell lung cancer (NSCLC) account for 85% of …

The Effect of Citrus aurantium on Non‐Small‐Cell Lung Cancer: A Research Based on Network and Experimental Pharmacology

L Yao, X Zhang, C Huang, Y Cai… - BioMed Research …, 2023 - Wiley Online Library
Purpose. To screen the main active components of Citrus aurantium through a network
pharmacology approach, construct a component‐disease target network, explore its …

Anthocyanins as modulators of cell redox-dependent pathways in non-communicable diseases

A Speciale, A Saija, R Bashllari… - Current medicinal …, 2020 - ingentaconnect.com
Chronic Noncommunicable Diseases (NCDs), mostly represented by cardiovascular
diseases, diabetes, chronic pulmonary diseases, cancers, and several chronic pathologies …

Berry anthocyanidins synergistically suppress growth and invasive potential of human non-small-cell lung cancer cells

H Kausar, J Jeyabalan, F Aqil, D Chabba, J Sidana… - Cancer letters, 2012 - Elsevier
Berry anthocyanidins (cyanidin, malvidin, peonidin, petunidin and delphinidin) have
increasingly been explored for their anticancer effects; however, their combinatorial effects …

Synergism Antiproliferative Effects of Apigenin and Naringenin in NSCLC Cells

X Liu, T Zhao, Z Shi, C Hu, Q Li, C Sun - Molecules, 2023 - mdpi.com
Non-small cell lung cancer (NSCLC) is one of the leading cancer killers. Apigenin (Api) and
Naringenin (Nar) are natural bioactive substances obtained in various vegetables and fruits …

The promising therapeutic and preventive properties of anthocyanidins/anthocyanins on prostate cancer

J Mottaghipisheh, AH Doustimotlagh, C Irajie… - Cells, 2022 - mdpi.com
As water-soluble flavonoid derivatives, anthocyanidins and anthocyanins are the plants
pigments mostly rich in berries, pomegranate, grapes, and dark color fruits. Many bioactivity …

The Pharmacological Mechanism of Curcumin against Drug Resistance in Non‐Small Cell Lung Cancer: Findings of Network Pharmacology and Bioinformatics …

H Xie, G Huang, J Zou, Q Zhu, Z Liang… - Evidence‐Based …, 2022 - Wiley Online Library
The pharmacological mechanism of curcumin against drug resistance in non‐small cell lung
cancer (NSCLC) remains unclear. This study aims to summarize the genes and pathways …