[HTML][HTML] Androgen receptor cofactors: A potential role in understanding prostate cancer

X Li, H Xiong, X Mou, C Huang, ER Thomas… - Biomedicine & …, 2024 - Elsevier
Prostate cancer (PCa) is witnessing a concerning rise in incidence annually, with the
androgen receptor (AR) emerging as a pivotal contributor to its growth and progression …

Regulating Androgen Receptor Function in Prostate Cancer: Exploring the Diversity of Post-Translational Modifications

LEV Lumahan, M Arif, AE Whitener, P Yi - Cells, 2024 - mdpi.com
Androgen receptor (AR) transcriptional activity significantly influences prostate cancer (PCa)
progression. In addition to ligand stimulation, AR transcriptional activity is also influenced by …

Androgen receptor cofactors in prostate cancer: potential therapeutic targets of castration-resistant prostate cancer

M Shiota, A Yokomizo, N Fujimoto… - Current cancer drug …, 2011 - ingentaconnect.com
Androgens, acting through the androgen receptor (AR), are responsible for many male
reproductive and nonreproductive functions. Moreover, aberrant androgen/AR signaling …

Androgen receptor coregulatory proteins as potential therapeutic targets in the treatment of prostate cancer

HV Heemers, DJ Tindall - Current cancer therapy reviews, 2005 - ingentaconnect.com
Prostate cancer (PCa) is the most frequently diagnosed cancer and the second leading
cause of cancer death in western men, and as such constitutes a significant health problem …

New Insights into the Androgen‐Targeted Therapies and Epigenetic Therapies in Prostate Cancer

AM Godbole, VCO Njar - Prostate cancer, 2011 - Wiley Online Library
Prostate cancer is the most common cancer in men in the United States, and it is the second
leading cause of cancer‐related death in American men. The androgen receptor (AR), a …

Androgen signaling in prostate cancer

C Dai, H Heemers, N Sharifi - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
The androgen-signaling axis plays a pivotal role in the pathogenesis of prostate cancer.
Since the landmark discovery by Huggins and Hodges, gonadal depletion of androgens has …

Androgen receptor co-regulation in prostate cancer

D Senapati, S Kumari, HV Heemers - Asian Journal of Urology, 2020 - Elsevier
Prostate cancer (PCa) progression relies on androgen receptor (AR) action. Preventing AR's
ligand-activation is the frontline treatment for metastatic PCa. Androgen deprivation therapy …

[图书][B] The Biological Role of Androgen Receptor in Prostate Cancer Progression

K Takayama - 2018 - books.google.com
Prostate cancer is the most commonly diagnosed cancer in men all over the world.
Localized cancers in the early stages can be well managed by surgical or radiation therapy …

[HTML][HTML] Posttranslational regulation of androgen dependent and independent androgen receptor activities in prostate cancer

S Wen, Y Niu, H Huang - Asian journal of urology, 2020 - Elsevier
Prostate cancer (PCa) is the most commonly diagnosed cancer among men in western
countries. Androgen receptor (AR) signaling plays key roles in the development of PCa …

[HTML][HTML] Androgen receptor and prostate cancer

KE Livermore, J Munkley, DJ Elliott - AIMS Molecular Science, 2016 - aimspress.com
Androgens play a key role in the development and progression of prostate cancer, and
androgen deprivation therapy (ADT) is the first line treatment for advanced disease …