Novel aspects of pathogenesis and regeneration mechanisms in COPD

E Bagdonas, J Raudoniute, I Bruzauskaite… - … journal of chronic …, 2015 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD), a major cause of death and morbidity
worldwide, is characterized by expiratory airflow limitation that is not fully reversible …

COPD: a multifactorial systemic disease

A Huertas, P Palange - Therapeutic advances in respiratory …, 2011 - journals.sagepub.com
Chronic obstructive pulmonary disease (COPD) has traditionally been considered a disease
of the lungs secondary to cigarette smoking and characterized by airflow obstruction due to …

Pathogenesis of chronic obstructive pulmonary disease

RM Tuder, I Petrache - The Journal of clinical investigation, 2012 - Am Soc Clin Investig
The current epidemic of chronic obstructive pulmonary disease (COPD) has produced a
worldwide health care burden, approaching that imposed by transmittable infectious …

Pathogenesis of inflammation and repair in advanced COPD

WD Cornwell, V Kim, C Song… - Seminars in respiratory …, 2010 - thieme-connect.com
Chronic obstructive pulmonary disease is characterized by an abnormal persistent
inflammatory response to noxious environmental stimuli, most commonly cigarette smoke …

Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction

KF Chung, IM Adcock - European Respiratory Journal, 2008 - Eur Respiratory Soc
Chronic obstructive pulmonary disease is a leading global cause of morbidity and mortality
that is characterised by inexorable deterioration of small airways obstruction with …

Animal models of COPD: W hat do they tell us?

B Jones, C Donovan, G Liu, HM Gomez… - …, 2017 - Wiley Online Library
ABSTRACT COPD is a major cause of global mortality and morbidity but current treatments
are poorly effective. This is because the underlying mechanisms that drive the development …

Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine

CA Brandsma, M Van den Berge… - The Journal of …, 2020 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a devastating lung disease with a high
personal and societal burden. Exposure to toxic particles and gases, including cigarette …

Lung epithelium damage in COPD–an unstoppable pathological event?

S Hadzic, CY Wu, S Avdeev, N Weissmann… - Cellular signalling, 2020 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a common term for alveolar septal wall
destruction resulting in emphysema, and chronic bronchitis accompanied by conductive …

New concepts in chronic obstructive pulmonary disease

PJ Barnes - Annual review of medicine, 2003 - annualreviews.org
Chronic obstructive pulmonary disease (COPD) is a leading cause of death and disability
but has only recently been explored from a cellular and molecular perspective. In COPD …

The pathology of chronic obstructive pulmonary disease

JC Hogg, W Timens - Annual Review of Pathology: Mechanisms …, 2009 - annualreviews.org
The pathogenesis of chronic obstructive pulmonary disease (COPD) is based on the innate
and adaptive inflammatory immune response to the inhalation of toxic particles and gases …