Allergic fungal rhinosinusitis (AFRS) is a highly resistant disease and is challenging to treat.
Patients with recurrent attacks of the disease despite surgical management can benefit from …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory condition
affecting the upper airways, with chronic symptoms such as nasal congestion, partial …

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) and type 2 asthma share
the same inflammatory pathophysiology and are frequent comorbidities. Dupilumab, a fully …

Background Biologic medications are increasingly incorporated into chronic rhinosinusitis
with nasal polyps (CRSwNP) management. However, little is known about prescribing …

Objectives To evaluate within‐patient symptom improvement in the dupilumab SINUS‐24/‐
52 studies in patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP) …

Herein we review the current literature on the adverse effects related to biological therapy
with the monoclonal antibody dupilumab in patients with type 2 inflammation prevalent …

Introduction Allergic fungal rhinosinusitis (AFRS) is a subtype of chronic rhinosinusitis with
nasal polyps. It is characterized by eosinophilic mucin, which results from an inflammatory …

Methods Adults with CRSwNP previously treated with systemic corticosteroids (SCS) and/or
surgery (n= 276) were randomized 1: 1 to subcutaneous dupilumab 300mg or placebo every …

Dupilumab has been shown to be safe and effective in treating chronic rhinosinusitis with
polyposis (CRSwNP). There is to this date no published data whether subgroups like …

Introduction: Chronic rhinosinusitis with nasal polyps (CRSwNP) affects 1–2.5% of the
population and is associated with significant adverse effects on quality of life (QoL) …