Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents

GC de Oliveira Santos, CC Vasconcelos… - Frontiers in …, 2018 - frontiersin.org
The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …

Emerging virulence, drug resistance and future anti-fungal drugs for Candida pathogens

V Srivastava, RK Singla… - Current topics in medicinal …, 2018 - ingentaconnect.com
Increased incidences of Candida infection have augmented morbidity and mortality in
human population, particularly among severely immunocompromised patients and those …

Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents

C Spampinato, D Leonardi - BioMed research international, 2013 - Wiley Online Library
The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …

Non-albicans Candida Species: Immune Response, Evasion Mechanisms, and New Plant-Derived Alternative Therapies

M Gómez-Gaviria, U Ramírez-Sotelo, HM Mora-Montes - Journal of Fungi, 2022 - mdpi.com
Fungal infections caused by Candida species have become a constant threat to public
health, especially for immunocompromised patients, who are considered susceptible to this …

[PDF][PDF] Virulence factors of Candida species

YL Yang - Journal of Microbiology Immunology and Infection, 2003 - thecandidadiet.com
Cellular immunity is the primary host defense against microbial infections. In the healthy
host, opportunistic fungal pathogens are commensal fungi commonly colonizing human …

[HTML][HTML] Drug resistance and novel therapeutic approaches in invasive candidiasis

SE Murphy, T Bicanic - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
Candida species are the leading cause of invasive fungal infections worldwide and are
associated with acute mortality rates of~ 50%. Mortality rates are further augmented in the …

Mechanism of Candida pathogenesis: revisiting the vital drivers

IE Mba, EI Nweze - European Journal of Clinical Microbiology & Infectious …, 2020 - Springer
Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …

[图书][B] Candida and candidiasis

RA Calderone, CJ Clancy - 2011 - books.google.com
The underlying mechanisms of Candida and candidiasis and promising new directions in
drug discovery and treatment.• Reviews all aspects of this common fungal pathogen and its …

Candidiasis and Mechanisms of Antifungal Resistance

S Bhattacharya, S Sae-Tia, BC Fries - Antibiotics, 2020 - mdpi.com
Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which
is caused by more than 20 types of Candida sp., with C. albicans being the most common …

Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond

Y Lee, E Puumala, N Robbins, LE Cowen - Chemical reviews, 2020 - ACS Publications
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …