The pursuit of polymethine fluorophores with NIR-II emission and high brightness for in vivo applications

X Zhao, F Zhang, Z Lei - Chemical Science, 2022 - pubs.rsc.org
Polymethine cyanine dyes, as the most important class of organic near-infrared-II (NIR-II)
fluorophores, recently received increasing attention due to their high molar extinction …

Molecular design of NIR-II polymethine fluorophores for bioimaging and biosensing

YF Ou, TB Ren, L Yuan, XB Zhang - Chemical & Biomedical …, 2023 - ACS Publications
Organic polymethine fluorophores with emission in the NIR-II window (1000–1700 nm) are
receiving enormous attention in biomolecular medicine and bioimaging, attributed to the …

Near-infrared-II cyanine/polymethine dyes, current state and perspective

Y Du, X Liu, S Zhu - Frontiers in Chemistry, 2021 - frontiersin.org
The development of near-infrared-II (NIR-II) fluorescence imaging has implemented real-
time detection of biological cells, tissues and body, monitoring the disease processes and …

Rational design of near-infrared-II organic molecular dyes for bioimaging and biosensing

B Li, M Zhao, F Zhang - ACS Materials Letters, 2020 - ACS Publications
In the past decade, fluorescence bioimaging in the second near-infrared (NIR-II, 1000–1700
nm) window has shown great potential in both fundamental research and preclinical …

Polymethine thiopyrylium fluorophores with absorption beyond 1000 nm for biological imaging in the second near-infrared subwindow

B Ding, Y Xiao, H Zhou, X Zhang, C Qu… - Journal of Medicinal …, 2018 - ACS Publications
Small-molecule fluorescence imaging in the second near-infrared (NIR-II, 1000–1700 nm)
window has gained increasing interest in clinical application. Till now, very few studies have …

Recent progress of cyanine fluorophores for NIR‐II sensing and imaging

HJ Zhou, TB Ren - Chemistry–An Asian Journal, 2022 - Wiley Online Library
The cyanine fluorophores, a kind of classic organic fluorophores, are famous for their high
extinction coefficient, simple synthetic route, and relatively long absorption and emission …

Counterion‐paired bright heptamethine fluorophores with NIR‐II excitation and emission enable multiplexed biomedical imaging

Y Yang, C Sun, S Wang, K Yan, M Zhao… - Angewandte …, 2022 - Wiley Online Library
Photon excitation and emission at the NIR‐II spectral window enable high‐contrast deep‐
tissue bioimaging. However, multiplexed imaging with NIR‐II excitation and emission has …

Research progress of near-infrared fluorescence probes based on indole heptamethine cyanine dyes in vivo and in vitro

C Sun, W Du, B Wang, B Dong, B Wang - BMC chemistry, 2020 - Springer
Near-infrared (NIR) fluorescence imaging is a noninvasive technique that provides
numerous advantages for the real-time in vivo monitoring of biological information in living …

Design strategies to rhodamine analogue fluorophores for near-infrared II biological imaging applications

C Liu, CN Scott - Dyes and Pigments, 2021 - Elsevier
Fluorescence imaging enables researchers to visualize a variety of biological tissues and
processes with high spatial and temporal resolution. Near-infrared II (NIR-II) dyes are more …

Repurposing cyanine NIR‐I dyes accelerates clinical translation of near‐infrared‐II (NIR‐II) bioimaging

S Zhu, Z Hu, R Tian, BC Yung, Q Yang… - Advanced …, 2018 - Wiley Online Library
The significantly reduced tissue autofluorescence and scattering in the NIR‐II region (1000–
1700 nm) opens many exciting avenues for detailed investigation of biological processes in …