[HTML][HTML] Perspective Chapter: Predictive Genomics

J Kriegsmann, S Cirovic, R Casadonte… - Electron Microscopes …, 2024 - intechopen.com
Predictive genomics can support treatment decisions by giving people the chance to act in
time to prevent serious illness. Tests based on single nucleotide polymorphism (SNP) can …

Single-nucleotide polymorphism analysis by MALDI–TOF mass spectrometry

TJ Griffin, LM Smith - Trends in biotechnology, 2000 - cell.com
Single-nucleotide polymorphisms (SNPs) have great potential for use in genetic-mapping
studies, which locate and characterize genes that are important in human disease and …

[PDF][PDF] Genotools SNP manager: a new software for automated high-throughput MALDI-TOF mass spectrometry SNP genotyping

W Pusch, KO Kraeuter, T Froehlich… - …, 2001 - pdfs.semanticscholar.org
Analysis of single nucleotide polymorphisms (SNPs) is a rapidly growing field of research
that provides insights into the most common type of differences between individual …

High throughput screening of genetic polymorphisms by matrix-assisted laser desorption ionization time-of-flight mass spectrometry

G Corona, G Toffoli - Combinatorial chemistry & high …, 2004 - ingentaconnect.com
In the post genomic era, the screening of many different genetic polymorphisms in large
populations represents a major goal that will facilitate the understanding of individual …

Mining disease susceptibility genes through SNP analyses and expression profiling using MALDI-TOF mass spectrometry

K Tang, P Oeth, S Kammerer… - Journal of Proteome …, 2004 - ACS Publications
To find genes that underlie disease susceptibilities, genome-wide single nucleotide
polymorphisms (SNPs) have been analyzed using high-throughput matrix assisted laser …

High‐throughput multiplex SNP genotyping with MALDI‐TOF mass spectrometry: practice, problems and promise

MS Bray, E Boerwinkle, PA Doris - Human mutation, 2001 - Wiley Online Library
Single nucleotide polymorphisms (SNPs) are currently being identified and mapped at a
remarkable pace, providing a rich genetic resource with vast potential for disease gene …

Detection of genetic variation by MALDI-TOF mass spectrometry: rapid SNP genotyping using the GENOLINK system

D Niemeyer, T Elssner, K Fahr, D Peters… - International Congress …, 2004 - Elsevier
Single nucleotide polymorphisms (SNPs) are the most common form of genetic variation in
the human genome. Because of their low mutation rate, SNPs have the potential to be as …

[HTML][HTML] GeenaR: a web tool for reproducible MALDI-TOF analysis

E Del Prete, A Facchiano, A Profumo, C Angelini… - Frontiers in …, 2021 - frontiersin.org
Mass spectrometry is a widely applied technology with a strong impact in the proteomics
field. MALDI-TOF is a combined technology in mass spectrometry with many applications in …

Technologies in the whole-genome age: MALDI-TOF-based genotyping

N Vogel, K Schiebel, A Humeny - Transfusion Medicine and …, 2009 - karger.com
With the decipherment of the human genome, new questions have moved into the focus of
today's research. One key aspect represents the discovery of DNA variations capable to …

Genotyping single nucleotide polymorphisms by MALDI mass spectrometry in clinical applications

J Tost, IG Gut - Clinical biochemistry, 2005 - Elsevier
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry
has become one of the most powerful and widely applied technologies for SNP scoring and …