[HTML][HTML] Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis

M Dapas, FTJ Lin, GN Nadkarni, R Sisk, RS Legro… - PLoS …, 2020 - journals.plos.org
Background Polycystic ovary syndrome (PCOS) is a common, complex genetic disorder
affecting up to 15% of reproductive-age women worldwide, depending on the diagnostic …

Genetics of polycystic ovary syndrome

TM Barber, S Franks - Polycystic ovary syndrome, 2013 - karger.com
Polycystic ovary syndrome (PCOS) is an oligogenic condition, with a heritability of∼ 70%.
PCOS is also associated with obesity, which itself is heavily influenced by genetic variants …

Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome

DA Dumesic, SE Oberfield, E Stener-Victorin… - Endocrine …, 2015 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a heterogeneous and complex disorder that has both
adverse reproductive and metabolic implications for affected women. However, there is …

Genetic studies on polycystic ovary syndrome

H Zhao, Y Lv, L Li, ZJ Chen - Best practice & research Clinical obstetrics & …, 2016 - Elsevier
Highlights•This paper sorts out most of the polycystic ovary syndrome (PCOS)-related
candidate genes and highlights some of the key genes.•A review of the results of recent …

[HTML][HTML] Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

F Day, T Karaderi, MR Jones, C Meun, C He… - PLoS …, 2018 - journals.plos.org
Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism,
ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have …

[HTML][HTML] The genetics of polycystic ovary syndrome: an overview of candidate gene systematic reviews and genome-wide association studies

D Hiam, A Moreno-Asso, HJ Teede, JSE Laven… - Journal of clinical …, 2019 - mdpi.com
Polycystic Ovary Syndrome (PCOS) is a complex condition with mechanisms likely to involve
the interaction between genetics and lifestyle. Familial clustering of PCOS symptoms is well …

Genetics of polycystic ovary syndrome

K Mykhalchenko, D Lizneva, T Trofimova… - Expert review of …, 2017 - Taylor & Francis
Introduction: Polycystic ovary syndrome (PCOS) is a hormonal and metabolic disorder
affecting 5 to 20% of reproductive-aged women worldwide that results in androgen excess …

Cross-ethnic meta-analysis of genetic variants for polycystic ovary syndrome

YV Louwers, L Stolk, AG Uitterlinden… - The Journal of Clinical …, 2013 - academic.oup.com
Context: Genome-wide association studies (GWAS) have revealed new susceptibility loci for
Chinese patients with polycystic ovary syndrome (PCOS). Because ethnic background adds …

Further investigation in europeans of susceptibility variants for polycystic ovary syndrome discovered in genome-wide association studies of Chinese individuals

MA Brower, MR Jones, JI Rotter… - The Journal of …, 2015 - academic.oup.com
Context: Two genome-wide association studies (GWAS) of polycystic ovary syndrome
(PCOS) have identified 11 susceptibility loci in Chinese individuals. Some of the risk loci …

[HTML][HTML] Polycystic ovarian syndrome: a complex disease with a genetics approach

H Nautiyal, SS Imam, S Alshehri, MM Ghoneim, M Afzal… - Biomedicines, 2022 - mdpi.com
Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder affecting females in
their reproductive age. The early diagnosis of PCOS is complicated and complex due to …