Targeting Key Players of Neuroendocrine Differentiation in Prostate Cancer
I Zamora, MR Freeman, IJ Encío, M Rotinen - International Journal of …, 2023 - mdpi.com
Neuroendocrine prostate cancer (NEPC) is a highly aggressive subtype of prostate cancer
(PC) that commonly emerges through a transdifferentiation process from prostate …
(PC) that commonly emerges through a transdifferentiation process from prostate …
Molecular mechanisms of neuroendocrine differentiation in prostate cancer progression
Y Xie, S Ning, J Hu - Journal of Cancer Research and Clinical Oncology, 2022 - Springer
Background Rapid evolution of the therapeutic management of prostate cancer, especially
in in second-generation androgen inhibitors, has increased the opportunity of transformation …
in in second-generation androgen inhibitors, has increased the opportunity of transformation …
Molecular events in neuroendocrine prostate cancer development
Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer. NEPC arises
de novo only rarely; the disease predominantly develops from adenocarcinoma in response …
de novo only rarely; the disease predominantly develops from adenocarcinoma in response …
Neuroendocrine differentiation of prostate cancer—An intriguing example of tumor evolution at play
Our understanding of neuroendocrine prostate cancer (NEPC) has assumed a new
perspective in light of the recent advances in research. Although classical NEPC is rarely …
perspective in light of the recent advances in research. Although classical NEPC is rarely …
The many faces of neuroendocrine differentiation in prostate cancer progression
In normal prostate, neuroendocrine (NE) cells are rare and interspersed among the
epithelium. These cells are believed to provide trophic signals to epithelial cell populations …
epithelium. These cells are believed to provide trophic signals to epithelial cell populations …
Understanding the molecular regulators of neuroendocrine prostate cancer.
S Bhattacharya, A Stillahn, K Smith… - Advances in Cancer …, 2024 - europepmc.org
Worldwide, prostate cancer (PCa) remains a leading cause of death in men. Histologically,
the majority of PCa cases are classified as adenocarcinomas, which are mainly composed …
the majority of PCa cases are classified as adenocarcinomas, which are mainly composed …
Neuroendocrine differentiation in prostate cancer: novel morphological insights and future therapeutic perspectives
M Santoni, A Conti, L Burattini, R Berardi… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Neuroendocrine prostate cancer (NEPC) is an aggressive variant of prostate cancer that
commonly arises in later stages of castration resistant prostate cancer (CRPC) The detection …
commonly arises in later stages of castration resistant prostate cancer (CRPC) The detection …
Clinical and biological features of neuroendocrine prostate cancer
Y Yamada, H Beltran - Current oncology reports, 2021 - Springer
Abstract Purpose of Review Neuroendocrine prostate cancer (NEPC) is an aggressive
histologic subtype of prostate cancer that most commonly arises in later stages of prostate …
histologic subtype of prostate cancer that most commonly arises in later stages of prostate …
Molecular mechanisms underlying the development of neuroendocrine prostate cancer
Prostate cancer is the most common non-cutaneous cancer and the second leading cause
of cancer-associated deaths among men in the United States. Androgen deprivation therapy …
of cancer-associated deaths among men in the United States. Androgen deprivation therapy …
[HTML][HTML] Advances in neuroendocrine prostate cancer research: From model construction to molecular network analyses
X Shui, R Xu, C Zhang, H Meng, J Zhao, C Shi - Laboratory investigation, 2022 - Elsevier
Prostate cancer is the most common cancer among men and has a high incidence and
associated mortality worldwide. It is an androgen-driven disease in which tumor growth is …
associated mortality worldwide. It is an androgen-driven disease in which tumor growth is …