Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

Programmed cell death plays critical roles in a wide variety of physiological processes
during fetal development and in adult tissues. In most cases, physiological cell death occurs …

Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable
manner, as a result of their immediate structural breakdown. Such an unavoidable variant of …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

Regulated cell death mediated by dedicated molecular machines, known as programmed
cell death, plays important roles in health and disease. Apoptosis, necroptosis and …

Naturally occurring cell death or apoptosis is essential for the maintenance of tissue
homeostasis and serves to remove extraneous or dangerous cells in a swift and unobtrusive …

Abstract In 2009, the Nomenclature Committee on Cell Death (NCCD) proposed a set of
recommendations for the definition of distinct cell death morphologies and for the …

Cell death is an essential phenomenon in normal development and homeostasis, but also
plays a crucial role in various pathologies. Our understanding of the molecular mechanisms …

Apoptosis represents a crucial process in modulating organ development in the embryo, in
organ homeostasis in the adult, and in fostering appropriate immunological function …

Unwanted cells are removed by physiological cell death processes that are highly
conserved throughout the animal kingdom. Physiological cell death plays an important role …