Molecular pathology and prostate cancer therapeutics: from biology to bedside

DN Rodrigues, LM Butler, DL Estelles… - The Journal of …, 2014 - Wiley Online Library
Prostate cancer (PCa) is the second most commonly diagnosed malignancy in men and has
an extremely heterogeneous clinical behaviour. The vast majority of PCas are hormonally …

Prostate cancer: pathophysiology, pathology and therapy

V Tzelepi - Cancers, 2022 - mdpi.com
Prostate cancer (PCa) is a major health care challenge in the developed world, being the
most common type of cancer in men in the USA [1] and most European countries [2] and the …

The molecular underpinnings of prostate cancer: impacts on management and pathology practice

DN Rodrigues, G Boysen… - The Journal of …, 2017 - Wiley Online Library
Prostate cancer (PCa) is a clinically heterogeneous disease and current treatment strategies
are based largely on anatomical and pathological parameters. In the recent past, several …

Updates on molecular and biochemical development and progression of prostate cancer

O Fahmy, NA Alhakamy, WY Rizg, A Bagalagel… - Journal of clinical …, 2021 - mdpi.com
Prostate cancer (PCa) represents the most commonly non-cutaneous diagnosed cancer in
men worldwide and occupies a very wide area of preclinical and clinical research. Targeted …

[HTML][HTML] Molecular pathology of prostate cancer: a practical approach

T Vlajnic, L Bubendorf - Pathology, 2021 - Elsevier
While localised prostate cancer can be cured by local treatment,'high-risk'prostate cancer
often progresses to castration resistant disease and remains incurable with a dismal …

Molecular therapeutics in prostate cancer

B Nicholson, D Theodorescu - Histology and histopathology, 2003 - digitum.um.es
The purpose of this review is to provide information on the molecular basis of prostate
cancer biology and to identify some of the targets for therapy, and highlight some potential …

Tumor microenvironment in prostate cancer: toward identification of novel molecular biomarkers for diagnosis, prognosis, and therapy development

HF Bahmad, M Jalloul, J Azar, MM Moubarak… - Frontiers in …, 2021 - frontiersin.org
Prostate cancer (PCa) is by far the most commonly diagnosed cancer in men worldwide.
Despite sensitivity to androgen deprivation, patients with advanced disease eventually …

Targeted therapy in prostate cancer

NM Corcoran, ME Gleave - Histopathology, 2012 - Wiley Online Library
Corcoran NM & Gleave ME (2012) Histopathology60, 216–231 Targeted therapy in prostate
cancer The therapeutic approach to advanced prostate cancer has seen greater changes in …

[图书][B] Precision molecular pathology of prostate cancer

BD Robinson, JM Mosquera, JY Ro, M Divatia - 2018 - Springer
Creating a diagnostic, prognostic, and therapeutic treatment strategy precisely tailored to
each patient's requirements is the fundamental idea behind precision medicine. The …

Unravelling the molecular mechanisms of prostate cancer evolution from genotype to phenotype

D Tong - Critical Reviews in Oncology/Hematology, 2021 - Elsevier
Prostate cancer (PC) is the most frequently diagnosed cancer and the second leading cause
of cancer-related death in men in the Western society. Unfortunately, although the vast …