High risk of cytomegalovirus infection following solid organ transplantation despite prophylactic therapy

H Harvala, C Stewart, K Muller, S Burns… - Journal of medical …, 2013 - Wiley Online Library
Cytomegalovirus infection (CMV) in solid organ transplant recipients is a major clinical
problem. The aim of this study was to evaluate the incidence of CMV infection and its …

[HTML][HTML] Importance of the cytomegalovirus seropositive recipient as a contributor to disease burden after solid organ transplantation

VC Emery, K Asher, C de Juan Sanjuan - Journal of clinical virology, 2012 - Elsevier
BACKGROUND: The incidence of cytomegalovirus (CMV) syndrome/disease after adult
solid organ transplantation in the era effective antiviral therapy has not been fully assessed …

Risk factors for late‐onset cytomegalovirus disease in donor seropositive/recipient seronegative kidney transplant recipients who receive antiviral prophylaxis

AA Boudreault, H Xie, RM Rakita… - Transplant Infectious …, 2011 - Wiley Online Library
AA Boudreault, H. Xie, RM Rakita, JD Scott, CL Davis, M. Boeckh, AP Limaye. Risk factors
for late‐onset cytomegalovirus disease in donor seropositive/recipient seronegative kidney …

[PDF][PDF] Prophylaxis versus preemptive therapy for cytomegalovirus disease in high‐risk liver transplant recipients

M Bodro, N Sabé, L Lladó, C Baliellas… - Liver …, 2012 - Wiley Online Library
Cytomegalovirus (CMV) infection is an opportunistic infection frequently found after solid
organ transplantation, and it contributes significantly to mortality and morbidity. CMV …

Cytomegalovirus infection in solid organ transplant recipients: new challenges and their implications for preventive strategies

N Singh - Journal of clinical virology, 2006 - Elsevier
BACKGROUND: Late-onset CMV disease is being increasingly recognized as a significant
post-transplantation complication. OBJECTIVES: To discern the impact of antiviral …

Successful prophylaxis of cytomegalovirus disease after primary CMV exposure in liver transplant recipients

RJ Stratta, MS Shaefer, KA Cushing, RS Markin… - …, 1991 - journals.lww.com
During a 38-month period, we studied 320 liver transplants in 283 recipients (202 adults, 81
children). CMV disease was documented in 85 patients (30.0%). The major risk factor for …

[HTML][HTML] Impact of antiviral preventive strategies on the incidence and outcomes of cytomegalovirus disease in solid organ transplant recipients

O Manuel, G Kralidis, NJ Mueller, HH Hirsch… - American journal of …, 2013 - Elsevier
We assessed the impact of antiviral prophylaxis and preemptive therapy on the incidence
and outcomes of cytomegalovirus (CMV) disease in a nationwide prospective cohort of solid …

Clinical utility of molecular surveillance for cytomegalovirus after antiviral prophylaxis in high-risk solid organ transplant recipients

LF Lisboa, JK Preiksaitis, A Humar, D Kumar - Transplantation, 2011 - journals.lww.com
Background. Cytomegalovirus (CMV) disease after discontinuation of prophylaxis is a
significant problem for CMV-seronegative recipients of CMV-seropositive organs (donor …

Risk factors for cytomegalovirus viremia and disease developing after prophylaxis in high-risk solid-organ transplant recipients

RB Freeman, C Paya, MD Pescovitz, A Humar… - …, 2004 - journals.lww.com
Background. Cytomegalovirus (CMV) D+/R− solid-organ transplant (SOT) recipients carry
increased risk of developing CMV disease; however, other risk factors in these patients have …

Allograft rejection predicts the occurrence of late-onset cytomegalovirus (CMV) disease among CMV-mismatched solid organ transplant patients receiving prophylaxis …

RR Razonable, A Rivero, A Rodriguez… - The Journal of …, 2001 - academic.oup.com
The natural history of cytomegalovirus (CMV) disease associated with solid organ
transplantation has been modified as a result of the widespread use of antiviral prophylaxis …