Ebola virus is a highly lethal pathogen responsible for several outbreaks of hemorrhagic
fever. Here we show that the primate lentiviral binding C-type lectins DC-SIGN and L-SIGN …

Ebola virus exhibits a broad cellular tropism in vitro. In humans and animal models, virus is
found in most tissues and organs during the latter stages of infection. In contrast, a more …

The lectins DC-SIGN and DC-SIGNR can augment viral infection; however, the range of
pathogens interacting with these attachment factors is incompletely defined. Here we show …

Abstract Background. The lectin DC-SIGN (dendritic cell-specific intercellular adhesion
molecule 3-grabbing nonintegrin) augments Ebola virus (EBOV) infection. However, it its …

The C-type lectins DC-SIGN and DC-SIGNR efficiently bind human immunodeficiency virus
(HIV) and simian immunodeficiency virus (SIV) strains and can transmit bound virus to …

Several Ebola viruses cause outbreaks of lethal haemorrhagic fever in humans, but
developing therapies tackle only Zaire Ebola virus. Dendritic cells (DCs) are targets of this …

ABSTRACT C-type lectins such as DC-SIGN and L-SIGN, which bind mannose-enriched
carbohydrate modifications of host and pathogen proteins, have been shown to bind …

Dendritic cells (DC) are vital in the defense against pathogens. To sense pathogens DC
express pathogen recognition receptors such as toll‐like receptors (TLR) and C‐type lectins …

The arenavirus Lassa virus (LASV) causes a severe hemorrhagic fever with high mortality in
humans. Antigen-presenting cells, in particular dendritic cells (DCs), are early and preferred …

Filoviruses cause lethal hemorrhagic disease in humans and nonhuman primates. An initial
target of filovirus infection is the mononuclear phagocytic cell. Calcium-dependent (C-type) …