[HTML][HTML] Enhancement of specialized metabolites using CRISPR/Cas gene editing technology in medicinal plants

S Das, M Kwon, JY Kim - Frontiers in Plant Science, 2024 - frontiersin.org
Plants are the richest source of specialized metabolites. The specialized metabolites offer a
variety of physiological benefits and many adaptive evolutionary advantages and frequently …

[HTML][HTML] Metabolic engineering of plant secondary metabolites: prospects and its technological challenges

A Mipeshwaree Devi, K Khedashwori Devi… - Frontiers in Plant …, 2023 - frontiersin.org
Plants produce a wide range of secondary metabolites that play vital roles for their primary
functions such as growth, defence, adaptations or reproduction. Some of the plant …

CRISPR/Cas9: a novel genetic tool to manipulate plant secondary metabolite pathways

M Arun, J Halka, K Kowsalya - … of Secondary Metabolites in Medicinal Plant, 2023 - Springer
The CRISPR/Cas9 gene editing method has brought a new era in genetic engineering and
genome research. However, CRISPR/Cas9 system incorporation has changed gene editing …

Genome editing in medicinal plants using CRISPR/Cas9 tool

BJ Naik, BMK Vasamsetti, SC Kim, M Gunti… - … Plant Metabolomics and …, 2023 - Springer
Medicinal plants have gained popularity in the medical field as herbal remedies due to their
beneficial secondary metabolites content. Secondary metabolites and derivatives are also in …

CRISPR/Cas genome editing in engineering plant secondary metabolites of therapeutic benefits

T Das, M Ghorai, DK Pandey, Radha, M Thakur… - Metabolic engineering in …, 2022 - Springer
Plants hold the ability to produce wide types of bioactive secondary metabolites. Having
emerged in the pregenomic era, increasingly more biosynthetic genes are being discovered …

CRISPR/Cas genome editing to optimize pharmacologically active plant natural products

A Dey - Pharmacological Research, 2021 - Elsevier
Since time immemorial, human use medicinal plants as sources of food, therapy and
industrial purpose. Classical biotechnology and recent next-generation sequencing (NGS) …

Genome editing technologies, mechanisms and improved production of therapeutic phytochemicals: Opportunities and prospects

S Mitra, U Anand, M Ghorai, N Kant… - Biotechnology and …, 2023 - Wiley Online Library
Plants produce a large number of secondary metabolites, known as phytometabolites that
may be employed as medicines, dyes, poisons, and insecticides in the field of medicine …

Nutraceuticals Enrichment by Genome Editing in Plants

LA Jiménez‐Ortega, JC Grimaldi‐Olivas… - Applications of …, 2024 - Wiley Online Library
Phytochemicals are secondary metabolites produced by plants that stand out for their
medicinal activities as antioxidants, antiobesogenic, hypoglycemic, antitumor …

CRISPR-based metabolic editing: Next-generation metabolic engineering in plants

M Sabzehzari, M Zeinali, MR Naghavi - Gene, 2020 - Elsevier
Plants generate many secondary metabolites, so called phyto-metabolites, which can be
used as toxins, dyes, drugs, and insecticides in bio-warfare plus bio-terrorism, industry …

CRISPR/Cas9-mediated genome editing in medicinal and aromatic plants: developments and applications

PA Shabir - Medicinal and aromatic plants, 2021 - Elsevier
Precise and straightforward methods to edit the plant genome have always been a
challenging area so as to provide more efficient ways for a meaningful change in the …