Atherosclerosis, which is the most common chronic disease of the coronary artery,
constitutes a vascular pathology induced by inflammation and plaque accumulation within …

Atherosclerosis, a multifactorial disease of large-and intermediate-sized arteries, is
characterized by the accumulation of lipids and the proliferation of arterial smooth muscle …

Underlying mechanisms of cardiovascular diseases (CVD) have been investigated for over
100 years and novel molecular level mechanisms in the pathophysiology are still …

Recent data support the involvement of epigenetic alterations in the pathogenesis of
atherosclerosis. The most widely investigated epigenetic mechanism is DNA methylation …

Atherosclerosis is a complex disease with involvement of intermediate-, large-sized arteries.
Atherosclerosis is characterized by the accumulation of vascular lipids, immune system …

Atherosclerosis is a vascular pathology characterized by inflammation and plaque build-up
within arterial vessel walls. Vessel occlusion, often occurring after plaque rupture, can result …

The vasculature not only transports oxygenated blood, metabolites, and waste products but
also serves as a conduit for hormonal communication between distant tissues. Therefore, it …

DNA methylation is a form of epigenetic modification of the genome that can regulate gene
expression. Hypermethylation of CpG islands in the promoter areas leads to decreased …

Significant progress has been made in the clinical management of a variety of
cardiovascular diseases. Nevertheless, the therapeutic efficacy of the current treatment …

Little is known about epigenetics and its possible role in atherosclerosis. We here analysed
histone and DNA methylation and the expression of corresponding methyltransferases in …