Recent studies have detailed the genomic landscape of primary endometrial cancers, but
the evolution of these cancers into metastases has not been characterized. We performed …

Endometrial cancer is the most common gynecological malignancy, with more than 280,000
cases occurring annually worldwide. Although previous studies have identified important …

Endometrial cancers are the most frequently diagnosed gynecological malignancy and were
expected to be the seventh leading cause of cancer death among American women in 2015 …

Endometrial cancer is the sixth most commonly diagnosed cancer in women worldwide,
causing∼ 74,000 deaths annually. Serous endometrial cancers are a clinically aggressive …

Clinicopathological evidence supports endometrial atypical hyperplasia (AH) or endometrial
intraepithelial neoplasia as the precursor of uterine endometrioid carcinoma (EC), the most …

BACKGROUND: Endometrial cancer is responsible for approximately 74 000 deaths
annually among women worldwide. It is a heterogeneous disease comprising multiple …

We performed an integrated genomic, transcriptomic and proteomic characterization of 373
endometrial carcinomas using array-and sequencing-based technologies. Uterine serous …

Recent advances in molecular studies, especially genome-wide analyses, have revealed
the landscape of genomic alterations present in endometrial carcinomas, and have provided …

All normal somatic cells are thought to acquire mutations, but understanding of the rates,
patterns, causes and consequences of somatic mutations in normal cells is limited. The …

Endometriosis is a common condition in women that causes chronic pain and infertility and
is associated with an elevated risk of ovarian cancer. We profiled transcriptomes of> …