Various attributes of micelles, such as PEG density and particle size, are considered to be
related to blood clearance. The structural stability of micelles is another key attribute that will …

Polymeric micelles hold great potential for anticancer drug delivery. Sufficient integrity of
polymeric micelles after intravenous injection is critical for successful drug delivery to solid …

Polymer micelles are one of the most investigated nanocarriers for drug delivery; many have
entered clinical trials and some are in clinic use, but their delivery systems have not yet …

Purpose Stability of polymeric micelles upon injection is essential for a drug delivery system
but is not fully understood. We optimized an analytical test allowing quantification of micellar …

Polymeric micelles (PM) have been extensively used for tumor‐targeted delivery of
hydrophobic anti‐cancer drugs. The lipophilic core of PM is naturally suitable for loading …

Micelles, as a class of drug delivery systems, are underrepresented among United States
Food and Drug Administration approved drugs. A lack of clinical translation of these systems …

Accelerated blood clearance (ABC) is a phenomenon where the blood clearance rate of the
carrier system is substantially raised. It can be induced by repetitive injections of …

Importance of the field: Spontaneously constructed from block copolymers in aqueous
media, the polymer micelle has been extensively studied as a potential carrier of poorly …

Micelles have been studied as drug delivery carriers for decades. Their use can potentially
result in high drug accumulation at the target site through the enhanced permeability and …

Block copolymer micelles have shown great potential in drug delivery systems, not only for
overcoming the drawbacks of small agents such as water insolubility and wide distribution in …