Increased Beta-Oxidation and Improved Oocyte Developmental Competence in Response to l-Carnitine During Ovarian In Vitro Follicle Development in Mice

KR Dunning, LK Akison, DL Russell… - Biology of …, 2011 - academic.oup.com
Oocyte developmental competence is acquired throughout folliculogenesis and is
associated with appropriate differentiation and responsiveness to the luteinizing hormone …

Promoting lipid utilization with l-carnitine to improve oocyte quality

KR Dunning, RL Robker - Animal reproduction science, 2012 - Elsevier
Successful embryo and fetal development is dependent on the quality of the oocyte from
which it was derived. Several studies to date have demonstrated the link between …

Beta-oxidation is essential for mouse oocyte developmental competence and early embryo development

KR Dunning, K Cashman, DL Russell… - Biology of …, 2010 - academic.oup.com
Oocyte and embryo metabolism are closely linked with their subsequent developmental
capacity. Lipids are a potent source of cellular energy, yet little is known about lipid …

Biological roles of l‐carnitine in oocyte and early embryo development

J Li, L Liu, J Weng, T Yin, J Yang… - Molecular Reproduction …, 2021 - Wiley Online Library
Poor oocyte quality is responsible for female infertility. Multiple studies have been carried
out to find supplements to enhance oocyte quality and mitigate infertility problems. l …

Lipids and oocyte developmental competence: the role of fatty acids and β-oxidation

KR Dunning, DL Russell, RL Robker - Reproduction, 2014 - research.monash.edu
Metabolism and ATP levels within the oocyte and adjacent cumulus cells are associated
with quality of oocyte and optimal development of a healthy embryo. Lipid metabolism …

l-Carnitine Supplementation During Vitrification of Mouse Oocytes at the Germinal Vesicle Stage Improves Preimplantation Development Following Maturation and …

AR Moawad, SL Tan, B Xu, HY Chen… - Biology of …, 2013 - academic.oup.com
Oocyte cryopreservation is important for assisted reproductive technologies (ART). Although
cryopreservation of metaphase II (MII) oocytes has been successfully used, MII oocytes are …

Effect of L-carnitine supplementation on maturation and early embryo development of immature mouse oocytes selected by brilliant cresyle blue staining

Z Zare, R Masteri Farahani, M Salehi, A Piryaei… - Journal of Assisted …, 2015 - Springer
Purpose The present study was designed to investigate the effect of L-carnitine treatment
during IVM on nuclear and cytoplasmic maturation of immature oocytes selected by Brilliant …

Carnitine content in the follicular fluid and expression of the enzymes involved in beta oxidation in oocytes and cumulus cells

D Montjean, F Entezami, I Lichtblau, S Belloc… - Journal of Assisted …, 2012 - Springer
Purpose The purpose of this study is to study lipid metabolism in oocytes and embryos that
is a neglected parameter in human IVF. Methods We have tested the total carnitine content …

Effect of oxidative stress during repeated ovulation on the structure and functions of the ovary, oocytes, and their mitochondria

K Miyamoto, EF Sato, E Kasahara, M Jikumaru… - Free Radical Biology …, 2010 - Elsevier
We previously reported that superoxide generated in the ovary induces apoptosis of
granulosa cells to break down follicular walls, thereby supporting ovulation in rodents, and …

Meiotic and developmental competence in mice are compromised following follicle development in vitro using an alginate-based culture system

MA Mainigi, T Ord, RM Schultz - Biology of reproduction, 2011 - academic.oup.com
Culture systems that support development and maturation of oocytes in vitro with a high
efficiency would have great impact not only on research addressed at underlying …