Strokes within pediatric populations are considered to be the 10th leading cause of death in
the United States of America, with over half of such events occurring in children younger …

The etiology of ischemic stroke is multifactorial. Although receiving less emphasis, genetic
causes make a significant contribution to ischemic stroke genesis, especially in early-onset …

Stroke in childhood has multiple etiologies, which are mostly distinct from those in adults.
Genetic discoveries over the last decade pointed to monogenic disorders as a rare but …

Stroke genetics includes several topics of clinical interest, including (1) molecular genetic
variations affecting risk of monogenic stroke syndromes;(2) molecular genetic variations …

Background: A substantial portion of stroke risk remains unexplained, and a contribution
from genetic factors is supported by recent findings. In most cases, genetic risk factors …

Stroke is the second leading cause of death and the most common cause of disability in the
world. Its incidence is rising with increasing life expectancy. To relieve the heavy burden of …

Stroke is a heterogeneous multifactorial disorder. Although epidemiological data from twin
and family studies provide substantial evidence for a genetic basis for stroke, the …

Introduction Stroke is one of the main causes of death and disability worldwide.
Nevertheless, despite the global burden of this disease, our understanding is limited and …

Stroke is the third leading cause of death and the leading cause of severe long-term
disability in developed countries. Despite significant progress in understanding the risk …

Epidemiologic evidence supports a genetic predisposition to stroke. Recent advances,
primarily using the genome-wide association study approach, are transforming what we …