Stress is an important factor in the development of several human pathologies. The
response of rodents and humans to stress depends on many factors; some people and …

Prolonged stressful events are an important risk factor for major depressive disorder.
However, there are dramatic individual variations in response to stress: a relatively small …

Viable new treatments for depression and anxiety have been slow to emerge, likely owing to
the complex and incompletely understood etiology of these disorders. A budding area of …

A majority of humans faced with severe stress maintain normal physiological and behavioral
function, a process referred to as resilience. Such stress resilience has been modeled in …

Research into the molecular basis of stress resilience is a novel strategy to identify potential
therapeutic strategies to treat stress-induced psychopathologies such as anxiety and …

There is an urgent need for more effective medications to treat major depressive disorder, as
fewer than half of depressed patients achieve full remission and many are not responsive …

Long-lasting stress factors, both biological and psychological, are commonly accepted as
the main cause of depressive disorders. Several animal models, using various stressful …

The term “resilience” refers to the ability to adapt successfully to stress, trauma and
adversity, enabling individuals to avoid stress-induced mental disorders such as depression …

There is significant variation in the way individuals react and respond to extreme stress and
adversity. While some individuals develop psychiatric conditions such as posttraumatic …

Background: Stress is a common reaction to an environmental adversity, but a dysregulation
of the stress response can lead to psychiatric illnesses such as major depressive disorder …