[HTML][HTML] Eosinophilic and noneosinophilic asthma: an expert consensus framework to characterize phenotypes in a global real-life severe asthma cohort

LG Heaney, LP de Llano, M Al-Ahmad, V Backer… - Chest, 2021 - Elsevier
Background Phenotypic characteristics of patients with eosinophilic and noneosinophilic
asthma are not well characterized in global, real-life severe asthma cohorts. Research …

[HTML][HTML] Allergic and eosinophilic asthma in the era of biomarkers and biologics: similarities, differences and misconceptions

J Oppenheimer, FCL Hoyte, W Phipatanakul… - Annals of Allergy …, 2022 - Elsevier
Objective Severe asthma is associated with substantial personal and economic burden;
maintaining disease control is the key management goal. Increased understanding of …

Overlap of allergic, eosinophilic and type 2 inflammatory subtypes in moderate‐to‐severe asthma

M Chen, K Shepard, M Yang, P Raut… - Clinical & …, 2021 - Wiley Online Library
Background Current biologic therapies target allergic, eosinophilic or type 2 inflammation
phenotypic asthma. However, frequency and degree of overlap among these subtypes is …

Severe eosinophilic asthma: a roadmap to consensus

R Buhl, M Humbert, L Bjermer… - European …, 2017 - Eur Respiratory Soc
Asthma is widely accepted as a complex heterogeneous condition with diverse
pathophysiological mechanisms, clinical presentations, comorbidities, physiological …

Asthma management: a new phenotype‐based approach using presence of eosinophilia and allergy

M Terl, V Sedlák, P Cap, R Dvořáková, V Kašák… - Allergy, 2017 - Wiley Online Library
Asthma is a heterogeneous disease. The Czech Pneumology and Allergology Societies
commissioned 10 experts to review the literature and create joint national guidelines for …

Eosinophilic and noneosinophilic asthma

TF Carr, AA Zeki, M Kraft - … journal of respiratory and critical care …, 2018 - atsjournals.org
The term “eosinophilic” asthma (EA) generally refers to the clinical inflammatory phenotype
of asthma wherein a significant number of sputum, airway, and/or blood eosinophils are …

Eosinophilic asthma

RK Nelson, A Bush, J Stokes, P Nair… - The Journal of Allergy and …, 2020 - Elsevier
Asthma endotypes are constantly evolving. Currently, there are no universally accepted
criteria to define endotypes. The TH 2-high endotype can have either allergic or nonallergic …

[HTML][HTML] Clinical characteristics and possible phenotypes of an adult severe asthma population

RM de Carvalho-Pinto, A Cukier, L Angelini… - Respiratory …, 2012 - Elsevier
BACKGROUND: Currently, there are no studies of well-characterized severe asthmatics in
Brazil. We aimed to study a population of severe treated asthmatics still uncontrolled to …

Clinical profile of patients with adult-onset eosinophilic asthma

JC de Groot, H Storm, M Amelink, SB de Nijs… - ERJ open …, 2016 - Eur Respiratory Soc
Adult-onset eosinophilic asthma is increasingly recognised as a severe and difficult-to-treat
subtype of asthma. In clinical practice, early recognition of patients with this asthma subtype …

Diagnosis and management of eosinophilic asthma: a US perspective

HH Walford, TA Doherty - Journal of asthma and allergy, 2014 - Taylor & Francis
Eosinophilic asthma is now recognized as an important subphenotype of asthma based on
the pattern of inflammatory cellular infiltrate in the airway. Eosinophilic asthma can be …