Background The interplay of epigenetic processes and the intestinal microbiota may play an
important role in intestinal development and homeostasis. Previous studies have …

The core human gut microbiota contributes to the developmental origin of diseases by
modifying metabolic pathways. To evaluate the predominant microbiota as an epigenetic …

Background DNA methylation is an epigenetic mechanism central to development and
maintenance of complex mammalian tissues, but our understanding of its role in intestinal …

Although much research has been done on the diversity of the gut microbiome, little is
known about how it influences intestinal homeostasis under normal and pathogenic …

Background DNA methylation is of pivotal importance during development. Previous
genome-wide studies identified numerous differentially methylated regions upon …

Preterm birth is the leading cause of infant morbidity and mortality. Necrotizing enterocolitis
(NEC) is an inflammatory bowel disease affecting primarily premature infants, which can be …

In recent years, the number of studies investigating the impact of the gut microbiome in
colorectal cancer (CRC) has risen sharply. As a result, we now know that various microbes …

Microbiota regulate intestinal physiology by modifying host gene expression along the
length of the intestine, but the underlying regulatory mechanisms remain unresolved …

Altered response to the intestinal microbiota strongly associates with inflammatory bowel
disease (IBD); however, how commensal microbial cues are integrated by the host during …

Background The gut microbiome, a key constituent of the colonic environment, has been
implicated as an important modulator of human health. The eukaryotic epigenome is …