Clinical and biological subtypes of B-cell lymphoma revealed by microenvironmental signatures
Diffuse large B-cell lymphoma (DLBCL) is a biologically and clinically heterogeneous
disease. Transcriptomic and genetic characterization of DLBCL has increased the …
disease. Transcriptomic and genetic characterization of DLBCL has increased the …
The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma
Biological heterogeneity in diffuse large B cell lymphoma (DLBCL) is partly driven by cell-of-
origin subtypes and associated genomic lesions, but also by diverse cell types and cell …
origin subtypes and associated genomic lesions, but also by diverse cell types and cell …
CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7 …
YH Huang, K Cai, PP Xu, L Wang, CX Huang… - … and Targeted Therapy, 2021 - nature.com
Epigenetic alterations play an important role in tumor progression of diffuse large B-cell
lymphoma (DLBCL). However, the biological relevance of epigenetic gene mutations on …
lymphoma (DLBCL). However, the biological relevance of epigenetic gene mutations on …
Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with recognized
variability in clinical outcome, genetic features, and cells of origin. To date, transcriptional …
variability in clinical outcome, genetic features, and cells of origin. To date, transcriptional …
Toward a new molecular taxonomy of diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) represents a grouping of clinically and biologically
heterogeneous tumors. Application of advanced molecular technology has significantly …
heterogeneous tumors. Application of advanced molecular technology has significantly …
Genetic and functional drivers of diffuse large B cell lymphoma
Diffuse large B cell lymphoma (DLBCL) is the most common form of blood cancer and is
characterized by a striking degree of genetic and clinical heterogeneity. This heterogeneity …
characterized by a striking degree of genetic and clinical heterogeneity. This heterogeneity …
Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes
Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive form of non-
Hodgkin lymphoma with variable biology and clinical behavior. The current classification …
Hodgkin lymphoma with variable biology and clinical behavior. The current classification …
Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease
B Chapuy, H Cheng, A Watahiki… - Blood, The Journal …, 2016 - ashpublications.org
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease defined by
transcriptional classifications, specific signaling and survival pathways, and multiple low …
transcriptional classifications, specific signaling and survival pathways, and multiple low …
Genetics and pathogenesis of diffuse large B-cell lymphoma
R Schmitz, GW Wright, DW Huang… - New England journal …, 2018 - Mass Medical Soc
Background Diffuse large B-cell lymphomas (DLBCLs) are phenotypically and genetically
heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B …
heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B …
Distinct biological subtypes and patterns of genome evolution in lymphoma revealed by circulating tumor DNA
Patients with diffuse large B cell lymphoma (DLBCL) exhibit marked diversity in tumor
behavior and outcomes, yet the identification of poor-risk groups remains challenging. In …
behavior and outcomes, yet the identification of poor-risk groups remains challenging. In …