Rate control of the tricarboxylic acid cycle
HA Krebs - Advances in enzyme regulation, 1970 - Elsevier
The rate of the tricarboxylic acid cycle is determined by the first step, the citrate synthase
reaction. The rate of this reaction depends on the concentrations of the two substrates …
reaction. The rate of this reaction depends on the concentrations of the two substrates …
[HTML][HTML] Control Mechanisms of Gluconeogenesis and Ketogenesis: II. Interactions between fatty acid oxidation and the citric acid cycle in perfused rat liver
JR Williamson, R Scholz, ET Browning - Journal of Biological Chemistry, 1969 - ASBMB
Previous work has shown that gluconeogenesis from a variety of substrates is stimulated by
oleate. This paper reports data on the effect of oleate on tissue levels of coenzyme A …
oleate. This paper reports data on the effect of oleate on tissue levels of coenzyme A …
The inhibition of citrate synthase by adenosine triphosphate
NO Jangaard, J Unkeless, DE Atkinson - Biochimica et Biophysica Acta …, 1968 - Elsevier
1. Citrate synthase (citrate oxaloacetate-lyase (CoA-acetylating), EC 4.1. 3.7) has been
partially purified from beef liver, beef heart and Escherichia coli. The beef heart and beef …
partially purified from beef liver, beef heart and Escherichia coli. The beef heart and beef …
Oxaloacetate metabolic crossroads in liver. Enzyme compartmentation and regulation of gluconeogenesis
R Marco, A Pestaña, J Sebastian, A Sols - Molecular and cellular …, 1974 - Springer
The subcellular distribution of the enzymes involved in oxaloacetate metabolism and certain
related enzymes in the liver of normal fed and starved rats has been studied. A simplified …
related enzymes in the liver of normal fed and starved rats has been studied. A simplified …
Enzymatic regulation of liver acetyl-CoA metabolism in relation to ketogenesis
O Wieland, L Weiss, I Eger-Neufeldt - Advances in Enzyme Regulation, 1964 - Elsevier
In the regulation of ketone body formation the citrate synthase reaction occupies a key
position in determining the metabolic fate of liver acetyl-CoA. As a factor which might shift …
position in determining the metabolic fate of liver acetyl-CoA. As a factor which might shift …
Ketogenesis in isolated rat liver mitochondria I. Relationships with the citric acid cycle and with the mitochondrial energy state
M Lopes-Cardozo, SG Van den Bergh - Biochimica et Biophysica Acta (BBA …, 1972 - Elsevier
A method is described to calculate the distribution of acetyl-CoA over the citric acid cycle
and ketogenesis during the oxidation of fatty acids in the presence of added malate. 2 …
and ketogenesis during the oxidation of fatty acids in the presence of added malate. 2 …
Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart
PJ Randle, PJ England, RM Denton - Biochemical Journal, 1970 - portlandpress.com
1. Transient and steady-state changes caused by acetate utilization were studied in
perfused rat heart. The transient period occupied 6min and steady-state changes were …
perfused rat heart. The transient period occupied 6min and steady-state changes were …
The calorigenic nature of hepatic ketogenesis: an explanation for the stimulation of respiration induced by fatty acid substrates
MN Berry, DG Clark, AR Grivell… - European journal of …, 1983 - Wiley Online Library
The rates of O2 consumption during fatty acid oxidation to acetyl‐CoA and to CO2 were
determined for isolated liver cells from starved rats on the basis of measured rates of …
determined for isolated liver cells from starved rats on the basis of measured rates of …
Control of citrate formation in rat liver mitochondria
JR Williamson, MS Olson, BE Herczeg… - … and Biophysical Research …, 1967 - Elsevier
Measurements of citrate formation and endogenous adenine nucleotides in fluorocitrate-
inhibited rat liver mitochondria respiring in the presence of 50 μM (−) palmitoyl carnitine and …
inhibited rat liver mitochondria respiring in the presence of 50 μM (−) palmitoyl carnitine and …
[引用][C] Citrate cleavage and acetate activation in livers of normal and diabetic rats
MS Kornacker, JM Lowenstein - … Acta (BBA)-Specialized Section on Lipids …, 1964 - Elsevier
The formation of acetyl-CoA from citrate can be regarded as the first step in the
extramitochondrial synthesis of fatty acidsZ, 2. Acetyl-CoA can also be formed from acetate …
extramitochondrial synthesis of fatty acidsZ, 2. Acetyl-CoA can also be formed from acetate …