Microbial dysbiosis tunes the immune response towards allergic disease outcomes

T Augustine, M Kumar, S Al Khodor… - Clinical Reviews in …, 2023 - Springer
The hygiene hypothesis has been popularized as an explanation for the rapid increase in
allergic disease observed over the past 50 years. Subsequent epidemiological studies have …

[HTML][HTML] New developments providing mechanistic insight into the impact of the microbiota on allergic disease

KD McCoy, Y Köller - Clinical immunology, 2015 - Elsevier
The increase in allergic diseases over the past several decades is correlated with changes
in the composition and diversity of the intestinal microbiota. Microbial-derived signals are …

Microbiome and allergic diseases

M Pascal, M Perez-Gordo, T Caballero… - Frontiers in …, 2018 - frontiersin.org
Allergic diseases, such as respiratory, cutaneous, and food allergy, have dramatically
increased in prevalence over the last few decades. Recent research points to a central role …

[HTML][HTML] Microbiome and the immune system: From a healthy steady-state to allergy associated disruption

S Mezouar, Y Chantran, J Michel, A Fabre… - Human Microbiome …, 2018 - Elsevier
Microbiome and the immune system are constantly shaping each other, in a mutual aim to
thrive, defining the unstable equilibrium of the healthy individual. Microbiome is growingly …

Antibiotics as instigators of microbial dysbiosis: implications for asthma and allergy

TP Wypych, BJ Marsland - Trends in immunology, 2018 - cell.com
The human body and its resident microbiota form a complex ecosystem, shaped by both
inherited and environmental factors. The use of antibiotics represents an extreme example …

The association between intestinal bacteria and allergic diseases—cause or consequence?

P Han, JQ Gu, LS Li, XY Wang, HT Wang… - Frontiers in Cellular …, 2021 - frontiersin.org
The incidence of allergic disorders has been increasing over the past few decades,
especially in industrialized countries. Allergies can affect people of any age. The …

The gut microbiota and its role in the development of allergic disease: a wider perspective

CE West, MC Jenmalm… - Clinical & Experimental …, 2015 - Wiley Online Library
The gut microbiota are critical in the homoeostasis of multiple interconnected host metabolic
and immune networks. If early microbial colonization is delayed, the gut‐associated …

The clinical implications of the microbiome in the development of allergy diseases

L Koidl, E Untersmayr - Expert Review of Clinical Immunology, 2021 - Taylor & Francis
Introduction: A substantial number of patients worldwide are affected by allergies. Emerging
evidence suggests that the individual microbial composition might contribute to the …

Dangerous liaisons: Bacteria, antimicrobial therapies, and allergic diseases

G Tramper‐Stranders, D Ambrożej, A Arcolaci… - Allergy, 2021 - Wiley Online Library
Microbiota composition and associated metabolic activities are essential for the education
and development of a healthy immune system. Microbial dysbiosis, caused by risk factors …

Microbiome/microbiota and allergies

Y Inoue, N Shimojo - Seminars in immunopathology, 2015 - Springer
Allergies are characterized by a hypersensitive immune reaction to originally harmless
antigens. In recent decades, the incidence of allergic diseases has markedly increased …