Combined utility of Ki-67 index and tumor grade to stratify patients with pancreatic ductal adenocarcinoma who underwent upfront surgery

B Li, X Yin, X Ding, G Zhang, H Jiang, C Chen, S Guo… - BMC surgery, 2023 - Springer
Objective To investigate the prognostic prediction of a new indicator, combined by tumor
grade and Ki-67, in patients with resected pancreatic ductal adenocarcinoma (PDAC) …

Prognostic impact of Ki-67 proliferative index in resectable pancreatic ductal adenocarcinoma

I Pergolini, S Crippa, M Pagnanelli, G Belfiori… - BJS open, 2019 - academic.oup.com
Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease
characterized by complex biological features and poor prognosis. A prognostic stratification …

[HTML][HTML] Prognostic significance of grade of malignancy based on histopathological differentiation and Ki-67 in pancreatic ductal adenocarcinoma

Y Liang, G Sheng, Y Guo, Y Zou, H Guo… - Cancer Biology & …, 2024 - ncbi.nlm.nih.gov
Objective: Tumor cell malignancy is indicated by histopathological differentiation and cell
proliferation. Ki-67, an indicator of cellular proliferation, has been used for tumor grading …

Preoperative prediction of long-term survival after surgery in patients with resectable pancreatic ductal adenocarcinoma

T Konishi, S Takano, T Takayashiki, D Suzuki… - Annals of Surgical …, 2024 - Springer
Background Although some clinical trials have demonstrated the benefits of neoadjuvant
therapy for resectable pancreatic ductal adenocarcinoma (PDAC), its optimal candidate has …

Validation of a proposed tumor regression grading scheme for pancreatic ductal adenocarcinoma after neoadjuvant therapy as a prognostic indicator for survival

SM Lee, MHG Katz, L Liu, M Sundar… - The American journal …, 2016 - journals.lww.com
Neoadjuvant therapy has been increasingly used to treat patients with potentially resectable
pancreatic ductal adenocarcinoma (PDAC). Although the College of American Pathologists …

The prognosis-based classification model in resectable pancreatic cancer

N Okui, M Tsunematsu, K Furukawa, Y Shirai, K Haruki… - Surgical Oncology, 2024 - Elsevier
Aim Pancreatic ductal adenocarcinoma treatment is mainly based on the anatomical
resectability classification. However, prognosis-based classification may be more …

Prognostic significance of new AJCC tumor stage in patients with pancreatic ductal adenocarcinoma treated with neoadjuvant therapy

D Chatterjee, MH Katz, WC Foo, M Sundar… - The American journal …, 2017 - journals.lww.com
Abstract The American Joint Committee for Cancer has adopted a size-based T stage
system (eighth edition) for pancreatic ductal adenocarcinoma (PDAC), defined as follows …

Morphologic changes associated with neoadjuvant-treated pancreatic ductal adenocarcinoma and comparison of two tumor regression grading systems

J Vazzano, WL Frankel, AR Wolfe, TM Williams… - Human Pathology, 2021 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is aggressive, with an overall five-year survival
rate of 9%, and few patients are candidates for pancreatectomy at presentation. The role of …

[HTML][HTML] A new staging system for postoperative prognostication in pancreatic ductal adenocarcinoma

Y Liang, J Cui, F Ding, Y Zou, H Guo, Q Man, S Chang… - Iscience, 2023 - cell.com
The current TNM staging system for pancreatic ductal adenocarcinoma (PDAC) has revised
the definitions of T and N categories as well as stage groups. However, studies validating …

Impact of tumor grade on pancreatic cancer prognosis: validation of a novel TNMG staging system

MM Rochefort, JS Ankeny, BE Kadera… - Annals of surgical …, 2013 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) patients demonstrate highly
variable survival within each stage of the American Joint Committee on Cancer (AJCC) …