Evaluation of a parasite-density based pooled targeted amplicon deep sequencing (TADS) method for molecular surveillance of Plasmodium falciparum drug …

S Louha, C Herman, M Gupta, D Patel, J Kelley… - Plos one, 2022 - journals.plos.org
Sequencing large numbers of individual samples is often needed for countrywide
antimalarial drug resistance surveillance. Pooling DNA from several individual samples is …

Pooled Deep Sequencing of Plasmodium falciparum Isolates: An Efficient and Scalable Tool to Quantify Prevailing Malaria Drug-Resistance Genotypes

SM Taylor, CM Parobek, N Aragam… - The Journal of …, 2013 - academic.oup.com
Molecular surveillance for drug-resistant malaria parasites requires reliable, timely, and
scalable methods. These data may be efficiently produced by genotyping parasite …

Next-generation sequencing and bioinformatics protocol for malaria drug resistance marker surveillance

E Talundzic, S Ravishankar, J Kelley… - Antimicrobial Agents …, 2018 - Am Soc Microbiol
The recent advances in next-generation sequencing technologies provide a new and
effective way of tracking malaria drug-resistant parasites. To take advantage of this …

Comparative analysis of targeted next-generation sequencing for Plasmodium falciparum drug resistance markers

C Kunasol, AM Dondorp, EM Batty, V Nakhonsri… - Scientific reports, 2022 - nature.com
Well-defined molecular resistance markers are available for a range of antimalarial drugs,
and molecular surveillance is increasingly important for monitoring antimalarial drug …

High throughput resistance profiling of Plasmodium falciparum infections based on custom dual indexing and Illumina next generation sequencing-technology

S Nag, MD Dalgaard, PE Kofoed, J Ursing, M Crespo… - Scientific reports, 2017 - nature.com
Genetic polymorphisms in P. falciparum can be used to indicate the parasite's susceptibility
to antimalarial drugs as well as its geographical origin. Both of these factors are key to …

Next generation whole genome sequencing of Plasmodium falciparum using NextSeq500 technology in India

A Mbengue, P Namdev, T Kumar, K Haldar… - bioRxiv, 2016 - biorxiv.org
Plasmodium falciparum is a protozoan parasite that causes the deadliest form of human
malaria. Although, malaria burdens worldwide have decreased substantially over the last …

Genetic diversity and drug resistance surveillance of Plasmodium falciparum for malaria elimination: is there an ideal tool for resource-limited sub-Saharan Africa?

TO Apinjoh, A Ouattara, VPK Titanji, A Djimde… - Malaria journal, 2019 - Springer
The intensification of malaria control interventions has resulted in its global decline, but it
remains a significant public health burden especially in sub-Saharan Africa (sSA) …

A method for amplicon deep sequencing of drug resistance genes in Plasmodium falciparum clinical isolates from India

PN Rao, S Uplekar, S Kayal, PK Mallick… - Journal of clinical …, 2016 - Am Soc Microbiol
ABSTRACT A major challenge to global malaria control and elimination is early detection
and containment of emerging drug resistance. Next-generation sequencing (NGS) methods …

Author Correction: Molecular surveillance of Plasmodium falciparum drug-resistance markers in Vietnam using multiplex amplicon sequencing (2000–2016)

E Rovira-Vallbona, JH Kattenberg, N Van Hong… - Scientific …, 2023 - ncbi.nlm.nih.gov
“The datasets (fastq files) generated and/or analyzed during the current study are available
in the NCBI Sequence Read Archive (SRA) repository under BioProject accession number …

Antimalarial drug resistance profiling of Plasmodium falciparum infections in India using Ion Torrent deep sequencing

S Kale, SM Uplekar, N Bandyopadhyay, PN Rao… - Frontiers in …, 2024 - frontiersin.org
Introduction Tracking the emergence and spread of antimalarial drug resistance is critical for
supporting progress towards the control and eventual elimination of malaria in South Asia …