Suppression of antitumor immune responses is one of the main mechanisms by which tumor
cells escape from destruction by the immune system. Myeloid-derived suppressor cells …

Myeloid-derived suppressor cells (MDSCs) are a heterogenic population of immature
myeloid cells with immunosuppressive effects, which undergo massive expansion during …

Myeloid-derived suppressor cells (MDSCs) are heterogeneous and poorly mature cells of
innate immunity that their population is increased substantially in cancer patients. MDSCs …

Myeloid cells developed evolutionarily as a major mechanism to protect the host. They
evolved as a critical barrier against infections and are important contributors to tissue …

Myeloid-derived suppressor cells (MDSCs) are one of the major negative regulators in tumor
microenvironment (TME) due to their potent immunosuppressive capacity. MDSCs are the …

Myeloid-derived suppressor cells (MDSCs) contribute to tumor-mediated immune escape
and negatively correlate with overall survival of cancer patients. Nowadays, a variety of …

The primary function of myeloid cells is to protect the host from infections. However, during
cancer progression or states of chronic inflammation, these cells develop into myeloid …

Among the various immunological and non-immunological tumor-promoting activities of
myeloid-derived suppressor cells (MDSCs), their immunosuppressive capacity remains a …

Anticancer agents continue to dominate the list of newly approved drugs, approximately half
of which are immunotherapies. This trend illustrates the considerable promise of cancer …

The immunosuppressive tumor microenvironment represents not only one of the key factors
stimulating tumor progression but also a strong obstacle for efficient tumor immunotherapy …