High-fat diet decreases energy expenditure and expression of genes controlling lipid metabolism, mitochondrial function and skeletal system development in the …

MS Choi, YJ Kim, EY Kwon, JY Ryoo, SR Kim… - British Journal of …, 2015 - cambridge.org
The aim of the present study was to identify the genes differentially expressed in the visceral
adipose tissue in a well-characterised mouse model of high-fat diet (HFD)-induced obesity …

Diet-induced obesity in ad libitum-fed mice: food texture overrides the effect of macronutrient composition

C Desmarchelier, T Ludwig, R Scheundel… - British journal of …, 2013 - cambridge.org
Diet-induced obesity in mice can be achieved through the use of diets with different
macronutrient compositions and textures. We aimed at determining the contribution of …

Energy‐restricted high‐fat diets only partially improve markers of systemic and adipose tissue inflammation

NS Kalupahana, BH Voy, AM Saxton… - …, 2011 - Wiley Online Library
This study aimed at investigating whether the weight loss due to energy‐restricted high‐fat
diets is accompanied with parallel improvements in metabolic markers and adipose tissue …

[HTML][HTML] Integrated multiomic analysis reveals the high-fat diet induced activation of the MAPK signaling and inflammation associated metabolic cascades via histone …

Z Wang, M Zhu, M Wang, Y Gao, C Zhang, S Liu… - Frontiers in …, 2021 - frontiersin.org
Background The number of diet induced obese population is increasing every year, and the
incidence of type 2 diabetes is also on the rise. Histone methylation and acetylation have …

[HTML][HTML] Nature of fatty acids in high fat diets differentially delineates obesity-linked metabolic syndrome components in male and female C57BL/6J mice

S El Akoum, V Lamontagne, I Cloutier… - Diabetology & metabolic …, 2011 - Springer
Background Adverse effects of high-fat diets (HFD) on metabolic homeostasis are linked to
adipose tissue dysfunction. The goal of this study was to examine the effect of the HFD …

High-fat diet leads to tissue-specific changes reflecting risk factors for diseases in DBA/2J mice

RS Hageman, A Wagener, C Hantschel… - Physiological …, 2010 - journals.physiology.org
The aim of this study was to characterize the responses of individual tissues to high-fat
feeding as a function of mass, fat composition, and transcript abundance. We examined a …

Genes are differentially expressed in the epididymal fat of rats rendered obese by a high-fat diet

YJ Kim, T Park - Nutrition research, 2008 - Elsevier
The aim of present study was to identify the visceral adipose tissue genes differentially
expressed in a well-characterized rat model of high-fat diet (HFD)–induced obesity. Male …

[HTML][HTML] Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during …

EY Kwon, SK Shin, YY Cho, UJ Jung, E Kim, T Park… - BMC genomics, 2012 - Springer
Background Visceral white adipose tissue (WAT) hypertrophy, adipokine production,
inflammation and fibrosis are strongly associated with obesity, but the time-course of these …

[HTML][HTML] High-fat diet-induced adipose tissue expansion occurs prior to insulin resistance in C57BL/6J mice

MQ He, JY Wang, Y Wang, J Sui, M Zhang… - Chronic Diseases and …, 2020 - Elsevier
Background To date, there is only scare evidence characterizing the temporal features and
progression of metabolic dysfunction in high-fat diet (HFD)-fed obese mice. Hence, its …

Shifts in diet from high fat to high carbohydrate improved levels of adipokines and pro-inflammatory cytokines in mice fed a high-fat diet

IS Lee, G Shin, R CHoUe - Endocrine journal, 2010 - jstage.jst.go.jp
High-fat diets induce an expansion of the adipose tissue (aT) that can be characterized by
chronic low-grade inflammation. AT is an important source of adipokines and pro …