[HTML][HTML] Anti-EGFR therapies in nasopharyngeal carcinoma

X Chen, R Liang, X Zhu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Nasopharyngeal carcinoma (NPC) is a common malignant tumor in Southern China and
South-East Asia. Regardless of initiative high response to radiotherapy, parts of patients still …

Novel systemic therapeutic for nasopharyngeal carcinoma

SL Chan, BB Ma - Expert Opinion on Therapeutic Targets, 2012 - Taylor & Francis
Introduction: Systemic therapy is crucial to the management of locally advanced or
metastatic nasopharyngeal cancer (NPC). Despite initial responses, the benefits of …

Prognostic role of epidermal growth factor receptor in nasopharyngeal carcinoma: a meta‐analysis

W Sun, G Long, J Wang, Q Mei, D Liu, G Hu - Head & Neck, 2014 - Wiley Online Library
Background Various studies have assessed the prognostic value of epidermal growth factor
receptor (EGFR) overexpression in nasopharyngeal carcinoma (NPC), but their results …

Phase II study of gefitinib for the treatment of recurrent and metastatic nasopharyngeal carcinoma

DTT Chua, WI Wei, MP Wong, JST Sham… - Head & Neck …, 2008 - Wiley Online Library
Background This single‐center, phase II study assessed the safety/tolerability and initial
efficacy of gefitinib in patients with nasopharyngeal carcinoma (NPC) pretreated with …

Novel therapy for nasopharyngeal carcinoma–where are we

J Tsang, VHF Lee, DLW Kwong - Oral oncology, 2014 - Elsevier
Nasopharyngeal carcinoma (NPC) is endemic in Southern China, and the South-East Asia
including Hong Kong. We still see patients recur after primary treatment with radiotherapy or …

Nimotuzumab, an anti-EGFR monoclonal antibody, in the treatment of nasopharyngeal carcinoma

R Liang, L Yang, X Zhu - Cancer Control, 2021 - journals.sagepub.com
Epidermal growth factor receptor (EGFR) is highly expressed in most of Nasopharyngeal
carcinoma (NPC) samples and is associated with poor outcomes. Therefore, targeting EGFR …

[HTML][HTML] Anti-EGFR targeted therapy delivered before versus during radiotherapy in locoregionally advanced nasopharyngeal carcinoma: a big-data, intelligence …

H Peng, LL Tang, X Liu, L Chen, WF Li, YP Mao… - BMC cancer, 2018 - Springer
Background Little is known about the prognostic difference of anti-EGFR therapy, cetuximab
(CTX) or nimotuzumab (NTZ), concurrently with induction chemotherapy (IC, investigational …

[HTML][HTML] Nasopharyngeal carcinoma: The role of the EGFR in epstein–barr virus infection

X Peng, Y Zhou, Y Tao, S Liu - Pathogens, 2021 - mdpi.com
Epstein–Barr virus (EBV), a type 4 γ herpes virus, is recognized as a causative agent in
nasopharyngeal carcinoma (NPC). Incidence of EBV-positive NPC have grown in recent …

Epidermal growth factor receptor could play a prognostic role to predict the outcome of nasopharyngeal carcinoma: a meta-analysis

X Ma, J Huang, X Wu, X Li, J Zhang, L Xue… - Cancer …, 2014 - content.iospress.com
Background: Epidermal growth factor receptor (EGFR) has been reported to play a
prognostic role in nasopharyngeal carcinoma (NPC). Nevertheless, the effect of EGFR …

Beneficial effects of anti-EGFR agents, Cetuximab or Nimotuzumab, in combination with concurrent chemoradiotherapy in advanced nasopharyngeal carcinoma

M Lin, R You, YP Liu, YN Zhang, HJ Zhang, X Zou… - Oral oncology, 2018 - Elsevier
Objective This study aimed to evaluate the efficacy and safety in locoregionally advanced
nasopharyngeal carcinoma (NPC) patients receiving concurrent chemoradiotherapy (CCRT) …