Compositions and methods of synthesis and use of novel nucleic acid structures

R Eritja, R Garcia - US Patent App. 10/966,672, 2006 - Google Patents
US20060008813A1 - Compositions and methods of synthesis and use of novel nucleic acid
structures - Google Patents US20060008813A1 - Compositions and methods of synthesis …

Method for the production of 2'-deoxyadenosine compounds

RK Robins, GR Revankar - US Patent 4,760,137, 1988 - Google Patents
A method that is direct and stereospecific is provided for the production of 2'-
deoxyadenosine derivatives and related analogs. The method comprises glycosylation of …

Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines

AR Moorman - US Patent 6,951,932, 2005 - Google Patents
The invention provides new methods for synthesis of 2-aralkyloxyadenosines and 2-
alkoxyadenosines. The invention is particularly useful for Synthesis of 2-2-(4-chlorophenyl) …

Process for the synthesis of oligonucleotides incorporating 2-aminoadenosine

BS Ross, M Manoharan - US Patent 6,175,004, 2001 - Google Patents
Kurtz Mackiewicz & Norris LLP (57) ABSTRACT This invention presents novel processes for
incorporating 2-aminoadenosine and 2-aminoadenosine analogs into oli gonucleotides. A …

Method of synthesizing adenosine, 2', 3'-o-isopropylidene-adenosine and intermediates thereof

K Suzuki, I Kumashiro - US Patent 3,450,693, 1969 - Google Patents
According to the present invention adenosine and 2', 3'-O-isopropylideneadenosine may be
produced in a series of reactions involving synthesis of 5-amino-4-cyano-1-(2', 3', 5'-tri-O …

Stable congener of 2', 3'-dideoxyadenosine

V Nair, GS Buenger - US Patent 5,013,829, 1991 - Google Patents
US5013829A - Stable congener of 2',3'-dideoxyadenosine - Google Patents US5013829A -
Stable congener of 2',3'-dideoxyadenosine - Google Patents Stable congener of 2',3'-dideoxyadenosine …

Nucleic Acid Related Compounds. LXXXI. Efficient General Synthesis of Purine (Amino, Azido, and Triflate)-Sugar Nucleosides

MJ Robins, SD Hawrelak, AE Hernández… - Nucleosides & …, 1992 - Taylor & Francis
Abstract Treatment of 3′, 5′-O-(tetraisopropyldisiloxanyl) adenosine and its arabino
epimer with trifluoromethanesulfonyl chloride/DMAP gave the 2′-triflates in high yields …

Process for preparing 2'-deoxy-β-adenosine

H Kawakami, H Matsushita, H Yoshikoshi… - US Patent …, 1993 - Google Patents
deoxy-β-adenosine can be industrially and easily obtained without using expensive or
dangerous materials by the process of the present invention, which comprises the steps of …

Deoxyadenosine compounds and methods of making and using the same

PD Cook, DJ McNamara - US Patent 4,908,441, 1990 - Google Patents
US4908441A - Deoxyadenosine compounds and methods of making and using the same -
Google Patents US4908441A - Deoxyadenosine compounds and methods of making and …

Intermediates useful in a synthesis of 2-chloro-2'-deoxyadenosine

RHK Chen - US Patent 5,208,327, 1993 - Google Patents
Processes for preparing 2-CdA are known. European Patent Application No. 173,059 A2
and R. Robins et al., J. Am. Chem. Soc, 106, 6379 (1984) disclose the prepa ration of 2-CdA …