Metabolic pathways, enzymes, and metabolites: Opportunities in cancer therapy
R Kumar, A Mishra, P Gautam, Z Feroz… - Cancers, 2022 - mdpi.com
Simple Summary Deregulated cellular metabolism is one of the major hallmarks of cancer.
Cancer cells orchestrate abnormal metabolic reprogramming to satisfy high energy …
Cancer cells orchestrate abnormal metabolic reprogramming to satisfy high energy …
Dysregulated metabolism in cancer
A Isa - Biomedical Research and Therapy, 2022 - biomedpress.org
Metabolism describes the cellular bioenergetic pathways that provide energy and
macromolecules for protein, lipid, and nucleic acid syntheses. In cancer, malignant cells …
macromolecules for protein, lipid, and nucleic acid syntheses. In cancer, malignant cells …
Recent advances in cancer metabolism: a technological perspective
YP Kang, NP Ward, GM DeNicola - Experimental & molecular medicine, 2018 - nature.com
Cancer cells are highly dependent on metabolic pathways to sustain both their proliferation
and adaption to harsh microenvironments. Thus, understanding the metabolic …
and adaption to harsh microenvironments. Thus, understanding the metabolic …
[HTML][HTML] Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies
Cancer cells are well documented to rewire their metabolism and energy production
networks to support and enable rapid proliferation, continuous growth, survival in harsh …
networks to support and enable rapid proliferation, continuous growth, survival in harsh …
Metabolic tricks of cancer cells
K Hönigova, J Navratil, B Peltanova… - … et Biophysica Acta (BBA …, 2022 - Elsevier
One of the characteristics of cancer cells important for tumorigenesis is their metabolic
plasticity. Indeed, in various stress conditions, cancer cells can reshape their metabolic …
plasticity. Indeed, in various stress conditions, cancer cells can reshape their metabolic …
Cancer Metabolism
MA Reid, SM Sanderson, JW Locasale - Abeloff's Clinical Oncology, 2020 - Elsevier
Cancer cells have different nutritional requirements from their normal counterparts, and
rewire their metabolism to support uncontrolled proliferation. In recent years, extensive study …
rewire their metabolism to support uncontrolled proliferation. In recent years, extensive study …
Metabolic reprogramming in cancer: Mechanisms and therapeutics
S Nong, X Han, Y Xiang, Y Qian, Y Wei, T Zhang… - MedComm, 2023 - Wiley Online Library
Cancer cells characterized by uncontrolled growth and proliferation require altered
metabolic processes to maintain this characteristic. Metabolic reprogramming is a process …
metabolic processes to maintain this characteristic. Metabolic reprogramming is a process …
[PDF][PDF] Therapeutic targeting of cancer cell metabolism: role of metabolic enzymes, oncogenes and tumor suppressor genes
Cancer cells compared to their normal counterparts reveal different metabolic needs and
this differential requirement of metabolic intermediates and their subsequent consequences …
this differential requirement of metabolic intermediates and their subsequent consequences …
Metabolic classification and intervention opportunities for tumor energy dysfunction
E Monferrer, I Vieco-Martí, A López-Carrasco, F Fariñas… - Metabolites, 2021 - mdpi.com
A comprehensive view of cell metabolism provides a new vision of cancer, conceptualized
as tissue with cellular-altered metabolism and energetic dysfunction, which can shed light …
as tissue with cellular-altered metabolism and energetic dysfunction, which can shed light …
Fundamentals of cancer metabolism
RJ DeBerardinis, NS Chandel - Science advances, 2016 - science.org
Tumors reprogram pathways of nutrient acquisition and metabolism to meet the
bioenergetic, biosynthetic, and redox demands of malignant cells. These reprogrammed …
bioenergetic, biosynthetic, and redox demands of malignant cells. These reprogrammed …