Next-generation sequencing shows the genomic features of ovarian clear cell cancer and compares the genetic architectures of high-grade serous ovarian cancer and …

M Gan, Z Tai, Y Yu, C Zhang, J Xu - PeerJ, 2023 - peerj.com
Ovarian clear cell carcinoma (OCCC) is a special histological type of epithelial ovarian
cancer (EOC) that is not derived from epithelial cells of the ovarian or fallopian tube as the …

Genomic landscape of ovarian clear cell carcinoma via whole exome sequencing

SI Kim, JW Lee, M Lee, HS Kim, HH Chung, JW Kim… - Gynecologic …, 2018 - Elsevier
Objective To analyze whole exome sequencing (WES) data on ovarian clear cell carcinoma
(OCCC) in Korean patients via the technique of next generation sequencing (NGS) …

[HTML][HTML] Genomic characterization of Chinese ovarian clear cell carcinoma identifies driver genes by whole exome sequencing

Q Yang, C Zhang, Y Ren, H Yi, T Luo, F Xing, X Bai… - Neoplasia, 2020 - Elsevier
Little is known about the genetic alterations characteristic of ovarian clear cell carcinoma
(OCCC). Our aim was to identify targetable genomic alterations in this type of cancer. Forty …

Systematic identification of characteristic genes of ovarian clear cell carcinoma compared with high-grade serous carcinoma based on RNA-sequencing

S Nagasawa, K Ikeda, K Horie-Inoue, S Sato… - International journal of …, 2019 - mdpi.com
Objective: Ovarian cancer has the highest mortality among gynecological cancers. High-
grade serous carcinoma (HGSC) is the most common histotype of ovarian cancer regardless …

Involvement of Chromatin Remodeling Genes and the Rho GTPases RhoB and CDC42 in Ovarian Clear Cell Carcinoma

NS Arildsen, JM Jönsson, K Bartuma… - Frontiers in …, 2017 - frontiersin.org
Objective Ovarian clear cell carcinomas (OCCCs) constitute a rare ovarian cancer subtype
with distinct clinical features, but may nonetheless be difficult to distinguish morphologically …

Genomic profiling of ovarian clear cell carcinoma in Chinese patients reveals potential prognostic biomarkers for survival

S Ye, S Zhou, Y Wu, X Pei, W Jiang, W Shi… - Annals of …, 2023 - Taylor & Francis
Introduction Ovarian clear cell carcinoma (OCCC) has distinct clinical and molecular
features and heterogeneous prognosis. Insights into the somatic genomic abnormalities of …

Integrated copy number and expression analysis identifies profiles of whole-arm chromosomal alterations and subgroups with favorable outcome in ovarian clear cell …

Y Uehara, K Oda, Y Ikeda, T Koso, S Tsuji… - PLoS …, 2015 - journals.plos.org
Ovarian clear cell carcinoma (CCC) is generally associated with chemoresistance and poor
clinical outcome, even with early diagnosis; whereas high-grade serous carcinomas (SCs) …

Molecular subclasses of clear cell ovarian carcinoma and their impact on disease behavior and outcomes

KL Bolton, D Chen, R Corona de la Fuente, Z Fu… - Clinical Cancer …, 2022 - AACR
Purpose: To identify molecular subclasses of clear cell ovarian carcinoma (CCOC) and
assess their impact on clinical presentation and outcomes. Experimental Design: We …

Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010

MS Anglesio, MS Carey, M Köbel, H MacKay… - Gynecologic …, 2011 - Elsevier
OBJECTIVES: Recent literature has highlighted histological types of ovarian carcinoma as
distinct diseases, each with unique clinical and molecular features. Historically, the …

[HTML][HTML] Exome sequencing landscape analysis in ovarian clear cell carcinoma shed light on key chromosomal regions and mutation gene networks

R Murakami, N Matsumura, JB Brown, K Higasa… - The American journal of …, 2017 - Elsevier
Previous studies have reported genome-wide mutation profile analyses in ovarian clear cell
carcinomas (OCCCs). This study aims to identify specific novel molecular alterations by …