Prognostic analysis and risk assessment based on RNA editing in hepatocellular carcinoma
X Shi, X Bu, X Zhou, N Shen, Y Chang, W Yu… - Journal of Applied …, 2024 - Springer
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, and
prognosis assessment is crucial for guiding treatment decisions. In this study, we aimed to …
prognosis assessment is crucial for guiding treatment decisions. In this study, we aimed to …
[HTML][HTML] Genomic identification of RNA editing through integrating omics datasets and the clinical relevance in hepatocellular carcinoma
RNA editing is a widespread post-transcriptional mechanism to introduce single nucleotide
changes to RNA in human cancers. Here, we characterized the global RNA editing profiles …
changes to RNA in human cancers. Here, we characterized the global RNA editing profiles …
A new prognostic model for accurate assessment of hepatocellular carcinoma risk using RNA editing data and unsupervised machine learning
H Zhu, H Zhang, Y Xiong, H Li - Neurocomputing, 2024 - Elsevier
Abstract A-to-I RNA editing is a long-known driving factor to the progression of
hepatocellular carcinoma (HCC); however, its importance is often neglected in HCC …
hepatocellular carcinoma (HCC); however, its importance is often neglected in HCC …
[HTML][HTML] A-to-I RNA co-editing predicts clinical outcomes and is associated with immune cells infiltration in hepatocellular carcinoma
J Chen, CH Zhang, T Tao, X Zhang, Y Lin… - Communications …, 2024 - nature.com
Aberrant RNA editing has emerged as a pivotal factor in the pathogenesis of hepatocellular
carcinoma (HCC), but the impact of RNA co-editing within HCC remains underexplored. We …
carcinoma (HCC), but the impact of RNA co-editing within HCC remains underexplored. We …
Identification of a novel DNA repair-related prognostic signature predicting survival of patients with hepatocellular carcinoma
N Li, L Zhao, C Guo, C Liu, Y Liu - Cancer management and …, 2019 - Taylor & Francis
Purpose Hepatocellular carcinoma (HCC) is the sixth most lethal neoplasm worldwide.
Traditional biomarkers often exploit the relationship between a certain gene and cancer …
Traditional biomarkers often exploit the relationship between a certain gene and cancer …
Epigenetic biomarkers for cancer risk stratification and patient management
The epigenome encompasses a compendium of heritable but potentially reversible
modifications that collectively regulate gene expression and drive development and cellular …
modifications that collectively regulate gene expression and drive development and cellular …
A new prognostic strategy based on four DNA repair-associated lncRNAs for hepatocellular carcinoma
H Zeng, C Liu, X Zhou, L Liu - Combinatorial Chemistry & High …, 2022 - ingentaconnect.com
Background: Hepatocellular carcinoma (HCC) is a malignant tumour with a poor prognosis.
The effect of DNA repair on prognosis cannot be ignored, and long non-coding RNA …
The effect of DNA repair on prognosis cannot be ignored, and long non-coding RNA …
[HTML][HTML] Mutational signatures representative transcriptomic perturbations in hepatocellular carcinoma
Q Wu, L Wang, SKW Tsui - Frontiers in Genetics, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is a primary malignancy with increasing incidence and
poor prognosis. Heterogeneity originating from genomic instability is one of the critical …
poor prognosis. Heterogeneity originating from genomic instability is one of the critical …
[HTML][HTML] Identification of DNA repair-related genes predicting pathogenesis and prognosis for liver cancer
W Zhu, Q Zhang, M Liu, M Yan, X Chu, Y Li - Cancer cell international, 2021 - Springer
Background Liver cancer (LC) is one of the most fatal cancers throughout the world. More
efficient and sensitive gene signatures that could accurately predict survival in LC patients …
efficient and sensitive gene signatures that could accurately predict survival in LC patients …
[HTML][HTML] Identification of a DNA damage repair-related LncRNA signature for predicting the prognosis and immunotherapy response of hepatocellular carcinoma
F Huang, C Zhang, W Yang, Y Zhou, Y Yang, X Yang… - BMC genomics, 2024 - Springer
Background DNA damage repair (DDR) may affect tumorigenesis and therapeutic response
in hepatocellular carcinoma (HCC). Long noncoding RNAs (LncRNAs) can regulate DDR …
in hepatocellular carcinoma (HCC). Long noncoding RNAs (LncRNAs) can regulate DDR …
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