[HTML][HTML] Plant-derived trimeric CO-26K-equivalent epitope induced neutralizing antibodies against porcine epidemic diarrhea virus

TT Ho, GT Nguyen, NB Pham, VP Le… - Frontiers in …, 2020 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) is a causative agent of a highly infectious disease
with a high mortality rate, especially in newborn piglets in Asian countries resulting in …

[HTML][HTML] The immunogenicity of plant-based COE-GCN4pII protein in pigs against the highly virulent porcine epidemic diarrhea virus strain from genotype 2

TT Ho, VT Trinh, HX Tran, PTT Le… - Frontiers in Veterinary …, 2022 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) is a serious infectious causative agent in swine,
especially in neonatal piglets. PEDV genotype 2 (G2) strains, particularly G2a, were the …

[HTML][HTML] Systemic and oral immunogenicity of porcine epidemic diarrhea virus antigen fused to poly-Fc of immunoglobulin G and expressed in ΔXT/ft Nicotiana …

NQD Tien, MS Yang, YS Jang, TH Kwon… - Frontiers in …, 2021 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV), a member of the Coronaviridae family has become
increasingly probelmatic in the pig farming industry. Currently, there are no effective …

Immunogenicity and protective efficacy of a trimeric full-length S protein subunit vaccine for porcine epidemic diarrhea virus

W Guo, C Wang, X Song, H Xu, S Zhao, J Gu, Z Zou… - Vaccine, 2024 - Elsevier
Porcine epidemic diarrhea virus (PEDV) has caused serious economic losses to the pig
husbandry worldwide, and the effects of existing commercialized vaccines are suboptimal …

[HTML][HTML] Oral recombinant Lactobacillus vaccine targeting the intestinal microfold cells and dendritic cells for delivering the core neutralizing epitope of porcine …

S Ma, L Wang, X Huang, X Wang, S Chen, W Shi… - Microbial Cell …, 2018 - Springer
Background Porcine epidemic diarrhea caused by porcine epidemic diarrhea virus (PEDV)
has led to serious economic losses to the swine industry worldwide. In this study, an oral …

[HTML][HTML] A novel CpG ODN compound adjuvant enhances immune response to spike subunit vaccines of porcine epidemic diarrhea virus

Y Wang, S Liu, B Li, X Sun, Q Pan, Y Zheng… - Frontiers in …, 2024 - frontiersin.org
CpG oligodeoxynucleotides (CpG ODNs) boost the humoral and cellular immune responses
to antigens through interaction with Toll-like receptor 9 (TLR9). These CpG ODNs have been …

[HTML][HTML] A therapeutic chimeric IgG/IgA expressed by CHO cells for oral treatment of PED in piglets

Y Xiao, Y Zhang, Z Wang, W Zhao, X Xu… - Frontiers in …, 2022 - frontiersin.org
Immunoglobulin A (IgA) of sows is critically important for assessing piglets' protective
capacity against porcine epidemic diarrhea virus (PEDV). Here, we report a therapeutic …

[HTML][HTML] Oral delivery of probiotics expressing dendritic cell-targeting peptide fused with porcine epidemic diarrhea virus COE antigen: a promising vaccine strategy …

X Wang, L Wang, X Huang, S Ma, M Yu, W Shi, X Qiao… - Viruses, 2017 - mdpi.com
Porcine epidemic diarrhea virus (PEDV), an enteric coronavirus, is the causative agent of
porcine epidemic diarrhea (PED) that damages intestinal epithelial cells and results in …

[HTML][HTML] Novel neutralizing epitope of PEDV S1 protein identified by IgM monoclonal antibody

T Thavorasak, M Chulanetra, K Glab-Ampai… - Viruses, 2022 - mdpi.com
Porcine epidemic diarrhea virus (PEDV) causes devastating enteric disease that inflicts
huge economic damage on the swine industry worldwide. A safe and highly effective PEDV …

[HTML][HTML] Generation and characterization of a spike glycoprotein domain A-specific neutralizing single-chain variable fragment against porcine epidemic diarrhea virus

CY Chang, YS Wang, JF Wu, TJ Yang, YC Chang… - Vaccines, 2021 - mdpi.com
The emergence of the genotype (G) 2 and re-emergence of the G1 porcine epidemic
diarrhea virus (PEDV) has caused severe economic impacts in the past decade …