Abstract Introduction Saturated fatty acids (FAs) are the main component of high‐fat diets
(HFDs), and high consumption has been associated with the development of insulin …

Palmitic acid (PA) is a saturated fatty acid whose high consumption has been largely
associated with the development of different metabolic alterations, such as insulin …

The prevalence of obesity and its co-morbidities such as insulin resistance and type 2
diabetes are tightly linked to increased ingestion of palatable fat enriched food. Thus, it …

The importance of fatty acids (FAs) for healthy brain development and function has become
more evident in the past decades. However, most studies focus on the hypothalamus as an …

Neurons spurn hydrogen-rich fatty acids for energizing oxidative ATP synthesis, contrary to
other cells. This feature has been mainly attributed to a lower yield of ATP per reduced …

Key points• We provide novel evidence for the effects of metabolic dysfunctions on brain
function using the rat model of metabolic syndrome induced by high fructose intake.• We …

It has been well recognized that intake of diets rich in saturated fats could result in
development of metabolic disorders such as type 2 diabetes mellitus, obesity and …

Obesity and metabolic syndrome are associated with cognitive decline and dementia.
Palmitic acid (PA) is increased in the cerebrospinal fluid of obese patients with cognitive …

Brain fatty acid (FA) metabolism deserves a close attention not only for its energetic aspects
but also because FAs and their metabolites/derivatives are able to influence many neural …

Consumption of high-fat diets (HFD) is associated with brain alterations, including changes
in feeding behavior, cognitive decline, and dementia. Astrocytes play a role in HFD-induced …