Enteroviruses and risk of islet autoimmunity or type 1 diabetes: systematic review and meta-analysis of controlled observational studies detecting viral nucleic acids …

SR Isaacs, A Roy, B Dance, EJ Ward… - The Lancet Diabetes & …, 2023 - thelancet.com
Background Enteroviruses are routinely detected with molecular methods within large
cohorts that are at risk of type 1 diabetes. We aimed to examine the association between …

Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies

WCG Yeung, WD Rawlinson, ME Craig - Bmj, 2011 - bmj.com
Objective To review the association between current enterovirus infection diagnosed with
molecular testing and development of autoimmunity or type 1 diabetes. Design Systematic …

Immunology in the clinic review series; focus on type 1 diabetes and viruses: the enterovirus link to type 1 diabetes: critical review of human studies

LC Stene, M Rewers - Clinical & Experimental Immunology, 2012 - academic.oup.com
Summary OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW
SERIES Metabolic diseases, host responses, cancer, autoinflammatory diseases, allergy …

Viruses and type 1 diabetes: from enteroviruses to the virome

SR Isaacs, DB Foskett, AJ Maxwell, EJ Ward… - Microorganisms, 2021 - mdpi.com
For over a century, viruses have left a long trail of evidence implicating them as frequent
suspects in the development of type 1 diabetes. Through vigorous interrogation of viral …

Enteroviruses and type 1 diabetes: multiple mechanisms and factors?

RE Lloyd, M Tamhankar… - Annual review of medicine, 2022 - annualreviews.org
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by insulin deficiency
and resultant hyperglycemia. Complex interactions of genetic and environmental factors …

Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY)

LC Stene, S Oikarinen, H Hyöty, KJ Barriga… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE To investigate whether enterovirus infections predict progression to type 1
diabetes in genetically predisposed children repeatedly positive for islet autoantibodies …

Association Between Enterovirus Infection and Type 1 Diabetes Risk: A Meta-Analysis of 38 Case-Control Studies

K Wang, F Ye, Y Chen, J Xu, Y Zhao… - Frontiers in …, 2021 - frontiersin.org
Objective The association between enterovirus infection and type 1 diabetes (T1D) is
controversial, and this meta-analysis aimed to explore the correlation. Methods PubMed …

Enterovirus infection and type 1 diabetes: unraveling the crime scene

T Rodriguez-Calvo - Clinical & Experimental Immunology, 2019 - academic.oup.com
Enteroviruses (EV) have been historically associated to type 1 diabetes. Definitive proof for
their implication in disease development is lacking, but growing evidence suggests that they …

Enteroviruses as causative agents in type 1 diabetes: loose ends or lost cause?

NG Morgan, SJ Richardson - Trends in Endocrinology & Metabolism, 2014 - cell.com
Considerable evidence implies that an enteroviral infection may accelerate or precipitate
type 1 diabetes (T1D) in some individuals. However, causality is not proven. We present and …

Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity

H Honkanen, S Oikarinen, N Nurminen, OH Laitinen… - Diabetologia, 2017 - Springer
Aims/hypothesis This case–control study was nested in a prospective birth cohort to
evaluate whether the presence of enteroviruses in stools was associated with the …